OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for OROPHARYNGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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Could less radiation be enough for HPV throat cancer?
Disease control OngoingThis study compares a reduced dose of radiation therapy combined with the immunotherapy drug nivolumab against the standard treatment of full-dose radiation plus cisplatin for early-stage HPV-positive oropharyngeal cancer in non-smokers. About 384 participants are enrolled to see…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 03:00 UTC
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Cancer trial aimed at clearing HPV after treatment pulled before starting
Disease control TerminatedThis study was designed for people with HPV-positive oropharyngeal cancer who still had signs of the virus in their blood after completing standard treatment. Researchers planned to give an immunotherapy drug called BALSTILIMAB to see if it could clear the virus and improve long-…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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New hope for throat cancer patients: smarter treatments on the horizon
Disease control OngoingThis study tests whether different drug combinations can improve survival and reduce side effects for people with intermediate or high-risk oropharyngeal (throat) cancer. About 785 participants will receive one of several experimental treatments alongside standard chemoradiothera…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: University of Birmingham • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Immunotherapy may replace chemo for some throat cancers
Disease control OngoingThis phase 2 trial compares standard treatment (radiation plus chemotherapy drug cisplatin) against two experimental arms using the immunotherapy drug durvalumab with radiation, followed by either durvalumab alone or durvalumab plus another immunotherapy, tremelimumab. The study …
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Canadian Cancer Trials Group • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Could your own muscle cells restore swallowing after cancer?
Disease control OngoingThis study tests if a person's own muscle cells, grown in a lab and injected into the tongue, can safely improve swallowing problems caused by head and neck cancer treatment. About 66 adults who finished cancer treatment at least 2 years ago and still have moderate swallowing tro…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Simple blood test could spot returning throat cancer sooner
Diagnosis OngoingThis study is testing a blood test that looks for HPV DNA in the blood of people treated for HPV-positive oropharyngeal cancer. The goal is to see if the test can find cancer recurrence earlier than standard follow-up methods. About 150 participants are being followed after treat…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Dana-Farber Cancer Institute • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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Could One-Sided radiation be safer for throat cancer patients?
Symptom relief OngoingThis study looks at whether people with throat cancer on one side of the neck can safely receive radiation to only that side, instead of both sides. The goal is to reduce side effects from unnecessary radiation. About 8 participants with early-stage HPV-related tonsil or tongue b…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New study aims to personalize throat cancer treatment using genetic tests and MRI
Knowledge-focused OngoingThis study looks at whether genetic markers (like tumor mutations and DNA in the blood) and special MRI scans can predict how well chemoradiotherapy works for patients with HPV-negative oropharyngeal cancer. Researchers will follow 30 patients to see if these tests can forecast t…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC