OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for OROPHARYNGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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New pill-chemo combo takes on hard-to-treat cancers
Disease control Not yet recruitingThis study tests a new drug called SX-682 (a tablet) combined with the chemotherapy docetaxel in people whose head/neck, salivary gland, or prostate cancer has spread or returned after treatment. The goal is to find the right dose and see if the combination shrinks tumors. About …
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 02, 2026 02:00 UTC
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Blood test could guide cancer treatment, reducing side effects
Disease control Not yet recruitingThis study tests whether a blood test that detects HPV DNA can help doctors choose the right treatment for people with HPV-positive oropharyngeal cancer. About 116 participants with stage I to III cancer will receive either the immunotherapy drug pembrolizumab (Keytruda) or stand…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New Vaccine-Drug combo aims to tame HPV throat cancer with less radiation
Disease control Not yet recruitingThis study tests a new treatment plan for people with HPV-positive oropharyngeal cancer (a type of throat cancer linked to HPV). The plan combines an immune-boosting drug (nogapendekin alfa inbakicept), a vaccine targeting HPV, chemotherapy, and a lower dose of radiation. The goa…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: ImmunityBio, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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New scan could spare throat cancer patients from unnecessary radiation side effects
Disease control Not yet recruitingThis study tests whether a special scan (SPECT-CT) can show which side of the neck needs radiation in people with oropharyngeal cancer. Currently, both sides are treated to prevent hidden cancer spread, but this causes more side effects. The trial will enroll 128 patients to see …
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: UNICANCER • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New combo therapy aims to personalize throat cancer treatment
Disease control Not yet recruitingThis study tests a new approach for people with a certain type of throat cancer that is not low-risk. Participants first receive a combination of chemotherapy, immunotherapy, and a special type of radiation called lattice radiotherapy. Then, based on how much the tumor shrinks, t…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Acupuncture timing may be key to preventing dry mouth in head and neck cancer patients
Symptom relief Not yet recruitingThis trial compares early versus delayed acupuncture to reduce dry mouth caused by chemoradiation in head and neck cancer patients. Participants receive acupuncture either during chemoradiation or after, and their dry mouth symptoms are tracked for a year. The goal is to find the…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: National University Hospital, Singapore • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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Could less radiation be just as effective for HPV throat cancer?
Symptom relief Not yet recruitingThis study is for people with HPV-related oropharyngeal (throat) cancer, which often responds well to treatment. The goal is to see if lowering the radiation dose to certain areas can reduce side effects like dry mouth without hurting the chance of curing the cancer. About 132 pa…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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AI to predict cancer risk from gut bacteria and scans
Knowledge-focused Not yet recruitingThis study will collect data from 10,000 people undergoing upper endoscopy to build an AI model that predicts the risk of developing stomach or esophageal cancer. Researchers will combine information from endoscopy images, tissue samples, genetics, and gut bacteria. Participants …
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC