OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Clinical trials for OROPHARYNGEAL SQUAMOUS CELL CARCINOMA explained in plain language.
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New combo therapy shows promise for Tough-to-Treat head and neck cancer
Disease control CompletedThis study tested whether giving the immunotherapy drug durvalumab alongside radiation works better than the standard cetuximab plus radiation for people with advanced head and neck cancer who cannot take the usual chemotherapy drug cisplatin. A total of 196 adults took part. The…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Major trial tests gentler radiation combo for HPV throat cancer
Disease control CompletedThis large phase 3 trial studied nearly 1,000 people with HPV-related oropharyngeal cancer to see if replacing chemotherapy with a targeted drug (cetuximab) during radiation could work as well or better. The goal was to find a treatment that controls the disease while possibly re…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: Radiation Therapy Oncology Group • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New scan could help doctors target neck cancer treatment more precisely
Diagnosis CompletedThis study tested whether injecting a radioactive tracer around oropharynx tumors and using SPECT-CT scans can map lymph node drainage. Twelve patients with oropharynx cancer participated. The goal was to see if this imaging method is practical and could help guide treatment deci…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: University Health Network, Toronto • Aim: Diagnosis
Last updated Jun 27, 2026 08:01 UTC
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Blood test may spot returning throat cancer earlier
Knowledge-focused CompletedThis completed study looked at whether circulating tumor cells (CTCs) in the blood can help predict or detect early return of oropharyngeal cancer. Researchers took blood samples from 12 patients at different times (diagnosis, after treatment, and during follow-up) and analyzed t…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Real-world data on keytruda and opdivo for HPV throat cancer could shape future trials
Knowledge-focused CompletedThis study looked at 662 patients with HPV-positive throat cancer that had spread or come back. Researchers wanted to see how patients were treated with pembrolizumab (Keytruda) or nivolumab (Opdivo), with or without chemotherapy, in real-world settings. The goal was to gather in…
Matched conditions: OROPHARYNGEAL SQUAMOUS CELL CARCINOMA
Sponsor: Hookipa Biotech GmbH • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:18 UTC