Could less radiation be safer? new trial aims to cut side effects after head and neck cancer surgery
NCT ID NCT07058805
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase II trial tests whether a personalized, reduced-volume radiation plan can safely lower side effects after surgery for head and neck cancer. About 50 patients will receive radiation only to high-risk areas, skipping some traditionally treated zones. The goal is to see if this approach keeps cancer from returning while reducing treatment burden.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Compartmentalized postoperative radiotherapy (radiation therapy tailored to each patient's risk)
- What this could lead to
- If successful, this approach could reduce side effects from radiotherapy after head and neck cancer surgery, making recovery easier without raising the risk of cancer coming back.
- What could go wrong
- This is a small, early-phase trial with only 50 participants, so results may not apply to everyone. There is a risk that omitting some radiation areas could lead to cancer recurrence in those spots.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Inselspital, Bern University Hospital
RECRUITINGBern, 3010, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital of Basel
RECRUITINGBasel, 4031, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospital of Zurich
RECRUITINGZurich, 8091, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
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