METASTATIC PANCREATIC ADENOCARCINOMA
Clinical trials for METASTATIC PANCREATIC ADENOCARCINOMA explained in plain language.
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New drug duo aims to starve tough pancreatic tumors
Disease control OngoingThis early-stage study is testing a new combination of two drugs, calaspargase pegol and cobimetinib, for people with advanced pancreatic cancer that has spread. The main goal is to find the safest and most effective dose. Researchers hope the two drugs will work together to cut …
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Apr 01, 2026 20:26 UTC
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New drug duo enters early trial for Tough-to-Treat digestive cancers
Disease control OngoingThis early-stage study is testing a combination of two drugs, guadecitabine and durvalumab, in people with advanced cancers of the liver, pancreas, bile duct, or gallbladder that have spread. The main goals are to find the safest dose and see what side effects occur. Researchers …
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE1 • Sponsor: University of Southern California • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New drug trial aims to keep aggressive pancreatic cancer in check
Disease control ENROLLING_BY_INVITATIONThis study is testing an experimental drug called DZ-002 as a maintenance therapy for adults with metastatic pancreatic cancer. The goal is to see if giving DZ-002 after successful initial chemotherapy can help control the cancer longer and prevent it from worsening. Researchers …
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Hoag Memorial Hospital Presbyterian • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New drug combo aims to keep deadly pancreatic cancer at bay
Disease control OngoingThis study is testing whether adding a new drug called ivaltinostat to a standard chemotherapy pill (capecitabine) can help control advanced pancreatic cancer for longer. It's for patients whose cancer has not gotten worse after initial treatment with a strong chemotherapy regime…
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: CG Pharmaceuticals, Inc • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New drug trial targets tough pancreatic cancer
Disease control OngoingThis early-stage study is testing the safety of a new drug, zolbetuximab, when given alongside standard chemotherapy to people with advanced pancreatic cancer that has spread. The drug works by attaching to a specific protein on cancer cells to help the immune system attack the t…
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Astellas Pharma Global Development, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New Immune-Targeting drug tested in fight against deadly pancreatic cancer
Disease control OngoingThis study is testing if adding a new drug called zolbetuximab to standard chemotherapy helps people with advanced pancreatic cancer that has spread. The drug works by targeting a specific protein found on many pancreatic cancer cells, aiming to help the immune system attack the …
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Astellas Pharma Global Development, Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New drug duo targets tough pancreatic cancer
Disease control OngoingThis early-stage trial is testing a combination of two oral drugs, binimetinib and hydroxychloroquine, for people with advanced pancreatic cancer that has a specific genetic change (KRAS mutation). The main goal is to find the safest and most effective dose of hydroxychloroquine …
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New drug cocktail tested in fight against tough cancers
Disease control OngoingThis early-stage study is testing the safety and best dose of a new drug called sEphB4-HSA when given alongside standard chemotherapy. It involves about 61 people with specific advanced or spreading cancers, including pancreatic, lung, and head/neck cancers, that have stopped res…
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE1 • Sponsor: University of Southern California • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Scientists test new drug duo to starve and stop advanced cancers
Disease control OngoingThis study is testing whether taking two oral drugs, cediranib and olaparib, together can help control advanced cancers that have spread or cannot be surgically removed. It is for adults with specific types of advanced lung, breast, or pancreatic cancer who have already tried at …
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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New hope for tough pancreatic cancers: adding a targeted drug to chemo
Disease control OngoingThis study is for people whose pancreatic cancer has spread and worsened after their first treatment. It compares a standard chemotherapy (FOLFIRI) against the same chemo plus an experimental drug called veliparib. The goal is to see if the combination helps patients live longer …
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Scientists test new drug cocktail in fight against tough pancreatic cancer
Disease control OngoingThis early-stage study is testing a combination of three drugs (gemcitabine, dasatinib, and erlotinib) in patients with advanced pancreatic cancer that has spread or cannot be surgically removed. The main goals are to find the safest and most effective dose and to understand the …
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Race against time: study tests which chemo combo helps older pancreatic cancer patients live longer
Disease control OngoingThis study aims to find out which of two standard chemotherapy combinations helps older adults with advanced pancreatic cancer that has spread live longer. It will enroll 176 patients aged 70 and older who have not yet received treatment for their metastatic cancer. Researchers w…
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Double attack on pancreatic cancer: can immune drug boost standard treatment?
Disease control OngoingThis study is for people with advanced pancreatic cancer that has spread and who have specific inherited BRCA gene mutations. It compares a standard maintenance drug (olaparib) alone against the same drug combined with an immunotherapy drug (pembrolizumab). The goal is to see if …
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Can enzyme pills help cancer patients keep weight on?
Symptom relief OngoingThis study is testing whether pancreatic enzyme replacement therapy (PERT) can help people with advanced pancreatic cancer maintain their body weight while on chemotherapy. Researchers are comparing two different dosing schedules of the enzyme supplement pancrelipase. The main go…
Matched conditions: METASTATIC PANCREATIC ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC