New hope for pancreatic cancer? early trial combines novel drug with chemo and immunotherapy
NCT ID NCT04104672
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a new drug called AB680, combined with immunotherapy (zimberelimab) and two chemotherapy drugs (nab-paclitaxel and gemcitabine), in people with advanced pancreatic cancer that has spread. The main goals are to check safety and find the right dose. About 196 participants who have not had prior treatment for metastatic disease will be enrolled.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research Site
Los Angeles, California, 90025, United States
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Research Site
Santa Monica, California, 90404, United States
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Research Site
St Louis, Missouri, 63110, United States
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Research Site
New York, New York, 10016, United States
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Research Site
New York, New York, 10032, United States
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Research Site
New York, New York, 10065, United States
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Research Site
Oklahoma City, Oklahoma, 73104, United States
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Research Site
Philadelphia, Pennsylvania, 19104, United States
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Research Site
Pittsburgh, Pennsylvania, 15232, United States
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Research Site
Nashville, Tennessee, 37203, United States
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Research Site
Houston, Texas, 77030, United States
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Research Site
San Antonio, Texas, 78229, United States
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Research Site
Madison, Wisconsin, 53792, United States