New drug combo aims to stall pancreatic cancer in maintenance therapy

NCT ID NCT05249101

First seen Jan 11, 2026 · Last updated May 06, 2026 · Updated 17 times

Summary

This study tests whether adding the experimental drug ivaltinostat to standard chemotherapy (capecitabine) can help control metastatic pancreatic cancer longer than chemo alone. It is for people whose cancer has not worsened after initial treatment with FOLFIRINOX. The trial has two parts: first finding the right dose, then randomly assigning 70 participants to either the combo or chemo alone.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Clinical Research Alliance

    Westbury, New York, 11590, United States

  • Community Health Network

    Indianapolis, Indiana, 46250, United States

  • Hoag Medical Group

    Newport Beach, California, 92663, United States

  • HonorHealth Research Institute

    Scottsdale, Arizona, 85258, United States

  • Norton Cancer Institute Audubon

    Louisville, Kentucky, 40217, United States

  • Penn State Hershey Cancer Institute

    Hershey, Pennsylvania, 17033, United States

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14263, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • The University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • UCLA Hematology/Oncology, Gastrointestinal Oncology

    Santa Monica, California, 90404, United States

  • UCSF Medical Center

    San Francisco, California, 94143, United States

  • University Cancer and Blood Center

    Athens, Georgia, 30607, United States

  • University Medical Center New Orleans

    New Orleans, Louisiana, 70112, United States

  • Utah Cancer Specialists

    Salt Lake City, Utah, 84107, United States

  • Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.