Experimental drug hopes to boost chemo against tough pancreatic cancer

NCT ID NCT03310632

Completed Disease control Sponsor: Golden Biotechnology Corporation Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This trial investigates whether adding antroquinonol (Hocena) to standard chemotherapy (nab-paclitaxel and gemcitabine) can safely treat people with metastatic pancreatic cancer that has not yet been treated. The study has two phases: first, finding the best dose, and second, checking how well the combination works. Participants must have stage IV pancreatic cancer and have not received prior systemic therapy for metastatic disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Antroquinonol (Hocena)
What this could lead to: If successful, this could offer a new combination treatment option for people with advanced pancreatic cancer.
What could go wrong: This is an early-phase trial with a small number of participants, so results may not confirm benefit. Side effects from the drug combination are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC NEOPLASM

Contacts and locations

Locations

Asan Medical Center

Seoul, 5505, South Korea
Cancer Treatment Centers of America - Eastern Regional Medical Center

Philadelphia, Pennsylvania, 19124, United States
Cancer Treatment Centers of America at Southeastern Regional Medical Center

Newnan, Georgia, 30265, United States
Florida Hospital Tampa

Tampa, Florida, 33613, United States
Henry Ford Health System

Detroit, Michigan, 48202, United States
Inha University Hospital

Incheon, 22322, South Korea
Maryland Oncology Hematology

Rockville, Pennsylvania, 20850, United States
National Cancer Center

Goyang-si, Gyeonggi-do, 10408, South Korea
National Cheng Kung University Hospital

Tainan, Tainan, 704, Taiwan
Severance Hospital, Yonsei University Health System

Seoul, 03722, South Korea
Taipei Veterans General Hospital

Taipei, Taipei, 11217, Taiwan

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