New drug cocktail aims to tame tough pancreatic cancer

NCT ID NCT05273554

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests whether combining two drugs, pembrolizumab (Keytruda) and lenvatinib, can help control advanced pancreatic cancer that has already been treated. Fifteen participants will receive the combination to see if it shrinks tumors. The goal is to gather initial data on effectiveness and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pembrolizumab (Keytruda) and lenvatinib

What this could lead to

If it works, this could point toward a new treatment option for advanced pancreatic cancer that has not responded to prior therapy.

What could go wrong

This is a very early, small pilot study with only 15 participants. The combination may not shrink tumors or improve survival, and side effects from the drugs could be significant.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adenocarcinoma neoplasm pancreatic adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States