TUMOR

This study is testing whether combining two drugs, nab-sirolimus (given by IV) and letrozole (a daily pill), can help control advanced or recurrent endometrial cancer. It is for patients whose cancer has returned or spread and who have had zero to one prior rounds of chemotherapy…

This study is testing an investigational drug called nirogacestat in adults with desmoid tumors, a rare type of non-cancerous but aggressive growth. The main goal is to understand why some people's tumors respond to the drug while others do not, by looking for specific biological…

This study is testing whether a combination of two drugs, obinutuzumab and CC-99282, can effectively control a specific type of blood cancer called follicular lymphoma in people who have not yet received any treatment for it. The trial is for adults with a high amount of cancer i…

This early-stage study aims to find a safe dose of the drug nab-sirolimus for adults with advanced solid tumors who also have moderate liver problems. It will compare how the drug is processed in the body between these patients and those with normal liver function. The main goal …

This study is testing whether a combination of two existing cancer drugs can help control tumors that have spread to the brain. It is enrolling about 104 adults with specific cancers, including triple-negative breast cancer and non-small cell lung cancer, that have spread to the …

This study is testing whether a combination of chemotherapy, immunotherapy, and radiation can effectively treat a rare form of muscle-invasive bladder cancer while allowing patients to keep their bladder. The treatment approach will be given to 20 participants with this specific …

This study aims to develop artificial intelligence tools to help doctors analyze capsule endoscopy videos. Capsule endoscopy involves swallowing a tiny camera that takes thousands of pictures of the digestive tract. The AI is designed to spot potential problems faster and more ac…

This study is testing a new type of PET/CT scan to see if it can better detect and measure areas of scarring (fibrosis) and tumors in the body. It will involve 30 participants, including patients with various diseases and healthy volunteers. The goal is to see if this imaging met…

This study is testing a new AI tool designed to help doctors during certain delicate stomach procedures. The tool highlights blood vessels on a screen in real-time, aiming to help the doctor spot and seal them to prevent bleeding and tears. The research will see if this AI assist…

This large international study is collecting information on a new, more precise type of radiation therapy that uses real-time MRI scans to guide treatment. It aims to see if this advanced technology helps people with many types of cancer live longer, better control their tumors, …

This study aims to understand why certain powerful cancer drugs (immune checkpoint inhibitors) can shrink tumors but sometimes cause serious heart problems. Researchers will follow 1,200 patients starting this therapy, analyzing their blood and genetics to find clues that predict…