Brain surgery gets a High-Tech helper: first human test of CIPHER system begins

NCT ID NCT07465796

Recruiting now Knowledge-focused Sponsor: Coherence Neuro Australia Pty Limited Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a new device called the CIPHER System, which records brain activity during surgery to remove a type of brain tumor called glioma. Ten adults with newly diagnosed glioma will have the device placed on their brain surface during standard tumor removal. The main goals are to check if the device is safe and if it can record brain signals properly. This is a data-gathering study, not a treatment trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CIPHER System (electrocorticography probe)
What this could lead to: If successful, this could lead to better tools for surgeons to identify tumor boundaries during brain surgery.
What could go wrong: This is a very early, small study (10 people) focused on safety and data collection, not treatment. The device may not improve outcomes or could cause side effects like seizures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain disorder glioma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN ELECTROCORTICOGRAPHY GLIOMA TUMOR

Contacts and locations

Locations

The Royal Melbourne Hospital, Department of Neurosurgery 4 East
RECRUITING

Melbourne, Victoria, 3050, Australia

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