New radiation method targets tough tumors
NCT ID NCT07645261
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests a new radiation technique called SBRT-LATTICE-PATHY for people with large tumors (at least 7 cm or 340 cm³) that cannot be treated with standard methods. The approach delivers a high dose of radiation only to low-oxygen areas inside the tumor, aiming to improve tumor control and reduce side effects. About 20 participants will be followed for 12 months to see if the tumor shrinks or stops growing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiation therapy (SBRT-LATTICE-PATHY)
- What this could lead to
- If it works, this could offer a new way to treat large tumors that are currently considered untreatable, potentially improving local control and survival.
- What could go wrong
- This is a small, early-phase trial with only 20 participants, so results may not apply broadly. The technique is new and risks like radiation toxicity or lack of benefit are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo - Instituto de Radiologia
RECRUITINGSão Paulo, São Paulo, 05403905, Brazil
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