METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Clinical trials for METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE explained in plain language.
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Gut bacteria capsule could tame fatty liver, early trial hopes
Disease control Recruiting nowThis early-stage study tests a probiotic capsule made from a pasteurized gut bacterium (Akkermansia muciniphila) in 40 adults with metabolic fatty liver disease (MASLD). The goal is to see if it safely reduces liver fat and scarring. Participants take different doses of the capsu…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: PHASE1 • Sponsor: Leeuwenhoek Laboratories Co. Ltd. • Aim: Disease control
Last updated May 17, 2026 12:57 UTC
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Can these drugs stop fatty liver from turning deadly? major trial launches
Disease control Recruiting nowThis study tests whether two medications, retatrutide and tirzepatide, can prevent major liver complications like cirrhosis, liver failure, or need for transplant in adults with high-risk metabolic fatty liver disease (MASLD). About 4,500 participants will receive either a drug o…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated May 17, 2026 12:46 UTC
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Period-Pausing drug may fight fatty liver in endometriosis patients
Disease control Recruiting nowThis study looks at whether a medication that temporarily stops menstruation (goserelin acetate) can reduce fat buildup in the liver of women with endometriosis. Researchers will measure liver fat and stiffness using ultrasound before and after treatment. The goal is to see if a …
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: PHASE4 • Sponsor: Aristotle University Of Thessaloniki • Aim: Disease control
Last updated May 17, 2026 12:46 UTC
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Could a gut antibiotic shrink fatty liver? new trial begins
Disease control Recruiting nowThis study tests whether rifaximin-α, an antibiotic that works in the gut, can reduce liver fat in people with metabolic fatty liver disease (MASLD). About 60 adults will take the drug or follow standard diet and exercise advice for 24 weeks. The goal is to see if the drug safely…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: EARLY_PHASE1 • Sponsor: Shanghai Changzheng Hospital • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New drug aims to shrink fatty liver in early trial
Disease control Recruiting nowThis study tests an experimental drug called ALN-CIDEB in adults with fatty liver disease (MASLD or MASH). The main goal is to check safety and side effects, and also see if it reduces liver fat. About 132 participants will receive either the drug or a placebo.
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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New hope for fatty liver: stomach procedure may beat diet alone
Disease control Recruiting nowThis study tests whether a minimally invasive stomach-shrinking procedure (endoscopic sleeve gastroplasty) combined with lifestyle changes is better than lifestyle changes alone for treating a serious liver condition called MASH in people with obesity. The procedure reduces stoma…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: NA • Sponsor: Pichamol Jirapinyo, MD, MPH • Aim: Disease control
Last updated May 11, 2026 20:49 UTC
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AI chatbot aims to curb alcohol use in fatty liver patients
Disease control Recruiting nowThis study tests whether a chatbot powered by large language models can help people with metabolic alcohol-related liver disease (MetALD) reduce their alcohol intake. About 50 adults in Hong Kong will use the chatbot for counseling. The goal is to see if the approach is practical…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: NA • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated May 08, 2026 12:00 UTC
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Could a simple ultrasound replace MRI for fatty liver diagnosis?
Diagnosis Recruiting nowThis study is testing a new ultrasound technique called DeepUSFF to see how well it measures liver fat compared to the current gold standard, MRI. About 62 adults with suspected fatty liver disease will get both scans. If successful, this could offer a faster, cheaper, and more a…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: NA • Sponsor: Seoul National University Hospital • Aim: Diagnosis
Last updated May 17, 2026 12:58 UTC
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Can a diet inspired by the mediterranean beat fatty liver in kids?
Symptom relief Recruiting nowThis study compares an Indianized version of the Mediterranean diet to a standard low-fat diet in overweight children and teens (ages 8-18) with a fatty liver condition called MASLD. The goal is to see which diet better reduces liver fat over 180 days. Participants will follow on…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: NA • Sponsor: Institute of Liver and Biliary Sciences, India • Aim: Symptom relief
Last updated May 17, 2026 12:57 UTC
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New alert system aims to catch liver damage early in primary care
Knowledge-focused Recruiting nowThis study tests a new computer alert that pops up in the electronic health record to remind doctors to check for liver scarring in patients with fatty liver disease. About 225 adults with fatty liver disease will take part. The goal is to see if the alert helps doctors find adva…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated May 17, 2026 12:45 UTC
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Fatty liver study probes hidden oxalate risk
Knowledge-focused Recruiting nowThis study looks at how much oxalate the body naturally makes in people with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), a type of fatty liver. About 28 adults with MASLD will eat a low-oxalate diet and provide urine samples to measure oxalate levels. The go…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Bariatric surgery study probes hidden cell signals behind fatty liver disease
Knowledge-focused Recruiting nowThis study looks at how tiny communication points inside liver cells (called MAMs) might be linked to a serious liver condition called MASH. Researchers will study 20 adults having weight-loss surgery to see if these cell changes affect disease progression. The goal is to better …
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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New registry aims to uncover hidden liver risks in diabetes patients
Knowledge-focused Recruiting nowThis study will follow 1000 adults with type 2 diabetes and fatty liver disease to understand how these conditions progress over time. Researchers will collect health data and blood samples to find markers that predict serious liver problems. The goal is to improve monitoring and…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC