Fatty liver gene hunt: could your DNA raise your risk?

NCT ID NCT07330830

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is looking at a specific gene, PNPLA3, in 600 adults with a type of fatty liver disease called MASLD. Participants are from Guadeloupe, French Guiana, and Réunion Island. Researchers want to see how common certain gene variants are and if they are linked to more severe liver problems. This is an observational study, not a treatment trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help identify genetic factors that make some people more likely to develop severe liver disease, potentially guiding future prevention or treatment strategies.

What could go wrong

This is an observational study that only looks at gene patterns, not testing a treatment. It may not lead directly to any new therapy, and results may not apply to other populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de la Guadeloupe

    RECRUITING

    Pointe-à-Pitre, 97159, Guadeloupe

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Universitaire de la Guyane

    NOT_YET_RECRUITING

    Cayenne, 97306, French Guiana

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Universitaire de la Réunion

    NOT_YET_RECRUITING

    Saint-Denis, 97400, Reunion

    Contact Phone: •••-•••-•••• Email: •••••@•••••