METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Clinical trials for METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE explained in plain language.
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Could a common b vitamin tame fatty liver?
Disease control Not yet recruitingThis trial tests whether a daily supplement of 5-methyltetrahydrofolate (a form of folate) can improve markers of liver health in people with metabolic dysfunction-associated steatotic liver disease (MASLD), a common type of fatty liver. Over 90 days, participants receive either …
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: NA • Sponsor: Tabriz University of Medical Sciences • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Ancient herb meets keto: new trial targets fatty liver
Disease control Not yet recruitingThis study tests whether a traditional Chinese medicine formula called Chazhu Xiaoli Formula (CXD), combined with a very low-carb (ketogenic) diet, can reduce liver fat in people with MASLD (fatty liver disease). 135 adults aged 18-50 will be randomly assigned to one of three gro…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: PHASE2 • Sponsor: Shanghai Municipal Hospital of Traditional Chinese Medicine • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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Could a gut bacteria byproduct help tame fatty liver in type 1 diabetes?
Disease control Not yet recruitingThis trial investigates whether a supplement called butyrate (a substance produced by gut bacteria) and an intensive lifestyle program (Mediterranean diet plus exercise) can reduce liver fat in adults with type 1 diabetes who also have fatty liver disease. Participants are random…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: NA • Sponsor: Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC
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Could a soy supplement help your liver? new trial investigates
Disease control Not yet recruitingThis phase 2 trial tests whether daidzein, a natural compound found in soy, can improve liver tissue health in adults with metabolic dysfunction-associated steatotic liver disease (MASLD). 44 participants scheduled for gallbladder surgery will take daidzein capsules or receive st…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: PHASE2 • Sponsor: Eastern Hepatobiliary Surgery Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New drug ACT500 targets dual liver disease in early trial
Disease control Not yet recruitingThis early-stage trial is testing a new drug called ACT500 in 24 people who have both fatty liver disease and chronic hepatitis B. The main goal is to check the drug's safety and how the body processes it at different doses. Participants will take ACT500 or a placebo daily, and r…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: PHASE1 • Sponsor: Xiamen Amoytop Biotech Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Morning or evening workout: which melts liver fat best?
Disease control Not yet recruitingThis study looks at whether exercising in the morning or evening makes a bigger difference in reducing liver fat for postmenopausal women with fatty liver disease. Sixty-three women will be placed into morning exercise, evening exercise, or a no-exercise group for 12 weeks. Resea…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: NA • Sponsor: Universidad de Almeria • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Could a bile acid pill in breast milk protect babies from liver problems?
Disease control Not yet recruitingThis study tests whether giving a bile acid pill (TUDCA) to breastfeeding mothers with fatty liver disease can make their breast milk healthier for their babies. Eighty mother-infant pairs will be randomly assigned to receive TUDCA or a placebo for a short time after birth. The g…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: PHASE2 • Sponsor: Peking University First Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New pill for fatty liver enters early human testing
Disease control Not yet recruitingThis early-stage study tests a new oral drug called ACT500 in 24 adults with fatty liver disease (MASLD). The main goal is to check safety and how the drug moves through the body. Participants take one pill daily in different dose groups. The study does not aim to cure the diseas…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: PHASE1 • Sponsor: Xiamen Amoytop Biotech Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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A needle-free way to detect fatty liver in kids? a new study puts a multi-test panel to the test.
Diagnosis Not yet recruitingThis study tests whether a combination of blood markers, ultrasound, and genetic information can accurately diagnose metabolic dysfunction-associated steatotic liver disease (MASLD) in children aged 8 to 18 with obesity. Each child provides a blood sample, undergoes a liver ultra…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Kayseri City Hospital • Aim: Diagnosis
Last updated Aug 01, 2026 00:00 UTC
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Could a simple scan and blood test outsmart liver cancer?
Knowledge-focused Not yet recruitingThis study looks at whether a structured surveillance program using regular ultrasound and a blood test (alpha-fetoprotein) can detect liver cancer at an earlier, more treatable stage in people at high risk. About 300 adults with liver cirrhosis, chronic hepatitis B, or advanced …
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: D'Or Institute for Research and Education • Aim: Knowledge-focused
Last updated Aug 16, 2026 00:00 UTC
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Can Weight-Loss surgery rewire the Liver's energy engine?
Knowledge-focused Not yet recruitingThis study looks at how bariatric surgery affects the liver's energy processing in people with obesity and fatty liver disease. Researchers will use safe, non-radioactive tracer infusions and MRI scans before, during, and six months after surgery to measure changes in liver metab…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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PCOS may fuel fatty liver in teens even after accounting for obesity — a study investigates
Knowledge-focused Not yet recruitingThis study explores whether polycystic ovary syndrome (PCOS) independently contributes to fatty liver disease in adolescent girls, beyond the effects of obesity. Researchers will compare three groups of girls aged 10–18: those with PCOS and obesity, those with obesity alone, and …
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Kayseri City Hospital • Aim: Knowledge-focused
Last updated Aug 01, 2026 00:00 UTC
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New MRI methods could spot liver damage earlier
Knowledge-focused Not yet recruitingThis study tests new MRI techniques to measure blood flow and tissue details in the liver. Researchers will scan 110 people, including healthy volunteers and those with chronic liver disease or fibrosis, to see if these scans can reliably detect liver damage. The goal is to devel…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jul 25, 2026 00:00 UTC
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Sleep apnea may signal hidden liver trouble
Knowledge-focused Not yet recruitingThis study investigates whether obstructive sleep apnea is linked to metabolic associated fatty liver disease (MAFLD) in adults. Researchers will measure sleep apnea severity using overnight sleep tests and liver fat using a special ultrasound-like scan. The goal is to see if wor…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC
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Fatty liver may be a hidden driver of heart attacks in diabetes
Knowledge-focused Not yet recruitingThis study follows 7,000 adults with type 2 diabetes and a common form of fatty liver disease (MASLD) to see how liver problems influence the risk of heart attacks, strokes, and heart failure. Researchers will track participants for five years, using advanced models to separate t…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: The Affiliated Hospital of Hangzhou Normal University • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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Blood tests may reveal fatty liver risks
Knowledge-focused Not yet recruitingThis study will check if certain blood-based inflammation markers are linked to fatty liver disease (MASLD) in 100 adults. Participants will have their blood tested and their liver health assessed. The goal is to better understand the role of inflammation in this condition, not t…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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When you eat may matter as much as what you eat, new study suggests
Knowledge-focused Not yet recruitingThis study will compare meal timing habits between 400 participants, including new mothers and people with fatty liver disease, along with healthy controls. Participants will complete diet diaries and questionnaires, with some undergoing additional tests like blood sugar monitori…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Maria Chondronikola • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Fatty liver patients: could a blood test spot heart attack risk?
Knowledge-focused Not yet recruitingThis study will check if a routine blood measure called mean platelet volume (MPV) can predict acute coronary syndrome (heart attack or unstable angina) in people with metabolic dysfunction-associated steatotic liver disease (MASLD). Researchers will compare MPV levels between 60…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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New ultrasound test could replace liver biopsies for fatty liver patients
Knowledge-focused Not yet recruitingThis study tests whether two different ultrasound machines can accurately measure liver stiffness and inflammation in people with fatty liver disease. About 95 to 100 adults will take part, including healthy liver donors and patients with fatty liver. The goal is to see if these …
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Seoul National University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Fatty liver study to reveal obesity link
Knowledge-focused Not yet recruitingThis study looks at 200 adults with fatty liver disease to find out how many are also obese. It will also describe the health details of patients who have fatty liver but are not overweight. The goal is to better understand the different types of fatty liver disease.
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Virtual twins could unlock secrets of fatty liver and heart risk
Knowledge-focused Not yet recruitingThis study aims to create detailed computer models, or 'virtual twins,' of people with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). By analyzing data from over 7,700 adults, researchers hope to better understand how the disease progresses and predict who migh…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: Hospital Universitari Vall d'Hebron Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Scientists probe whether cutting insulin levels can curb liver fat
Knowledge-focused Not yet recruitingThis study looks at how lowering insulin levels changes the way the liver makes sugar and fat. Researchers will give 36 overweight or obese adults with insulin resistance and fatty liver disease two different insulin infusions—one that keeps insulin high and one that lowers it by…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Phase: PHASE1 • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Can ultrasound replace MRI for fatty liver diagnosis?
Knowledge-focused Not yet recruitingThis study will test whether a special ultrasound technique can measure liver stiffness and fat as accurately as MRI in people with fatty liver disease. Researchers will compare results from both imaging methods in 145 healthy volunteers and patients. The goal is to find a simple…
Matched conditions: METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE
Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC