New drug ACT500 targets dual liver disease in early trial
NCT ID NCT07589400
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial is testing a new drug called ACT500 in 24 people who have both fatty liver disease and chronic hepatitis B. The main goal is to check the drug's safety and how the body processes it at different doses. Participants will take ACT500 or a placebo daily, and researchers will monitor for side effects and measure drug levels in the blood.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ACT500 tablets
- What this could lead to
- If successful, this could point toward a new treatment option for people with both fatty liver disease and chronic hepatitis B.
- What could go wrong
- This is an early Phase 1 trial with only 24 participants, so it is primarily testing safety and dosing. It is too early to know if ACT500 will be effective or have significant side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Beijing Friendship Hospital, Capital Medical University
Beijing, China
-
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China
-
The First Affiliated Hospital of Xinjiang Medical University
Ürümqi, China
-
Xiamen Hospital of Traditional Chinese Medicine
Xiamen, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a new injection tame chronic hepatitis b?
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