Exercise may fight fatty liver by targeting hidden muscle fat

NCT ID NCT06506513

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial investigates whether different intensities of physical exercise can reduce fat stored in muscles (myosteatosis) and improve liver health in people with metabolic dysfunction-associated steatotic liver disease (MASLD). Researchers will compare high-intensity interval training, moderate intensity exercise, and low intensity exercise over several weeks. The goal is to see if reducing muscle fat can help treat the liver condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
exercise training (high-intensity interval training, moderate intensity, or low intensity)
What this could lead to
If successful, this could show that tailored exercise programs are an effective way to treat fatty liver disease by targeting muscle fat.
What could go wrong
This is a small, early-stage trial with 60 participants, so results may not apply to everyone. It is also unclear which exercise intensity works best or if benefits last long-term.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre d'investigation clinique en nutrition

    RECRUITING

    Louvain-la-Neuve, 1348, Belgium

    Contact

    Contact Email: •••••@•••••

  • Cliniques universitaires Saint-Luc

    RECRUITING

    Brussels, 1200, Belgium

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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