Gut bacteria boost may help fight fatty liver

NCT ID NCT07400367

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a multi-strain probiotic supplement, taken alongside standard lifestyle advice, can improve liver health in people with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). The trial will enroll 80 adults with elevated liver enzymes and fatty liver. Participants will receive either the probiotic or a placebo for 12 weeks, and researchers will measure changes in liver stiffness (fibrosis), fat content, and metabolic risk factors like blood sugar and cholesterol.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

multi-strain probiotic (Lactobacillus salivarius AP-32, Lactobacillus rhamnosus bv-77, Bifidobacterium animalis CP-9, Lactobacillus reuteri GL-104)

What this could lead to

If it works, this could point toward a simple, safe add-on treatment to help manage MASLD and reduce liver damage.

What could go wrong

This is a small, early-stage trial (80 people) testing a dietary supplement, not a drug. Results may not be dramatic or apply to everyone, and the effect on liver fibrosis is still uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver fatty liver disease Insulin Resistance metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fu Jen Catholic University Hospital

    NOT_YET_RECRUITING

    New Taipei City, Taiwan

  • Fu Jen Catholic University Hospital

    RECRUITING

    New Taipei City, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••