Gut bacteria boost may help fight fatty liver
NCT ID NCT07400367
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether a multi-strain probiotic supplement, taken alongside standard lifestyle advice, can improve liver health in people with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). The trial will enroll 80 adults with elevated liver enzymes and fatty liver. Participants will receive either the probiotic or a placebo for 12 weeks, and researchers will measure changes in liver stiffness (fibrosis), fat content, and metabolic risk factors like blood sugar and cholesterol.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- multi-strain probiotic (Lactobacillus salivarius AP-32, Lactobacillus rhamnosus bv-77, Bifidobacterium animalis CP-9, Lactobacillus reuteri GL-104)
- What this could lead to
- If it works, this could point toward a simple, safe add-on treatment to help manage MASLD and reduce liver damage.
- What could go wrong
- This is a small, early-stage trial (80 people) testing a dietary supplement, not a drug. Results may not be dramatic or apply to everyone, and the effect on liver fibrosis is still uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fu Jen Catholic University Hospital
NOT_YET_RECRUITINGNew Taipei City, Taiwan
-
Fu Jen Catholic University Hospital
RECRUITINGNew Taipei City, Taiwan
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