INFLUENZA

This study looks at how getting the flu vaccine year after year changes your body's immune response. Researchers are testing two types of flu vaccines—a nasal spray (FluMist) and a shot (Flublok)—in 600 adults aged 22 to 50 in Hong Kong. They will measure antibodies and immune ce…

This study tests a nasal spray flu vaccine in 200 people aged 3 to 17. Researchers will measure specific antibodies in the nose to see how well the vaccine works. The goal is to understand the immune response and improve flu prevention.

This large study enrolled over 15,000 U.S. military members to compare three types of licensed flu vaccines: egg-based, recombinant, and cell-culture-based. Participants were randomly assigned to one of the three vaccines over four flu seasons. The main goal is to see which vacci…

This early-stage trial is testing whether a new flu vaccine with an adjuvant (a booster ingredient) is safe for adults aged 65 and older. Eighty volunteers will receive a single shot and be monitored for side effects over a year. The study does not yet test if the vaccine prevent…

This early-stage trial is testing the safety of a new quadrivalent influenza vaccine with an adjuvant (a booster ingredient) in adults aged 65 and older. Eighty participants will receive either the new vaccine, a standard flu vaccine, or a placebo. The study monitors side effects…

This study compares high-dose and standard-dose flu vaccines in 396 adults who received a kidney, heart, or liver transplant within the past year. The goal is to see if a higher dose or two doses provide better protection against the flu. Results will help improve vaccine recomme…

This study tests a single dose of a new flu vaccine called OVX836 in about 2,850 healthy adults aged 18 to 59. The goal is to see if it can prevent confirmed influenza A and how safe it is. Participants will be randomly assigned to receive either the vaccine or a placebo.

This study looks at how a nasal flu vaccine works in 60 healthy teenagers aged 14-17. Researchers will measure immune responses in the nose and blood before and after a single dose. The goal is to understand how the vaccine protects against the flu.

This study tests whether a single injection of peramivir can safely treat uncomplicated flu in adults. Participants receive either 150 mg, 300 mg of peramivir, or a placebo, and researchers measure how quickly symptoms improve. The goal is to see if this antiviral shot offers a f…

This study tests a simple, at-home smell test to see if it can detect COVID-19 infection and track how smell recovers over time. About 1000 adults, including those with known smell loss and healthy volunteers, will use smell cards to rate odor intensity, identification, and discr…

This study tests two new devices (imPulse Una and TOR) that use sound waves to detect COVID-19, flu, and RSV without needles or swabs. About 300 adults with or without symptoms will have a quick, painless scan. The goal is to see if these e-stethoscopes can accurately identify th…

This phase 3 trial is testing whether a single dose of CD388, a long-acting antiviral injection, can prevent the flu in 10,000 adults and teens at higher risk of complications. Participants receive either CD388 or a placebo and are monitored for flu-like illness over 24 weeks. Th…

This study compares a 5-day versus a 10-day course of oseltamivir (Tamiflu) to prevent influenza in people exposed to the virus while in the hospital. About 200 adults with flu risk factors will be randomly assigned to one of the two treatment lengths. The goal is to see if the s…

This study tests whether a community-based communication program can increase flu vaccination rates among people over 65 in Can Tho City, Vietnam. The program includes direct counseling, weekly health tips via the Zalo app, and printed leaflets. Researchers will compare vaccinati…

This study tests different text message reminders to see which ones work best at getting people to get their flu vaccine. About 100,000 patients who haven't had their flu shot yet will receive a reminder text before a doctor's visit. The goal is to find simple, effective ways to …

This study planned to test a single IV dose of peramivir against placebo in teens and adults with uncomplicated flu. The goal was to see if it could shorten flu symptoms like cough, sore throat, and fever. However, the trial was withdrawn before any participants were enrolled, so…

This early-stage study tests different doses of an experimental flu medicine called TRX-100, taken alongside standard care, in 105 people with mild to moderate influenza. The main goals are to check safety and find the best dose. Researchers will also track how well it eases flu …

This study tracks 80 adults with different smell disorders (like total loss, partial loss, or distorted smell) plus healthy volunteers over one year. Researchers use brain scans, smell tests, and questionnaires to see how the brain changes and how smell loss impacts mood and dail…

This study tests a new AI-powered toolkit designed to help public health officials at local CDC offices respond more quickly to emerging infectious diseases such as COVID-19, mpox, influenza, and dengue. The toolkit combines data analysis, risk assessment, decision support, and e…

This study tests whether training primary care providers on how to talk to patients about vaccines can increase flu and COVID-19 vaccination rates. Over 24,500 patients and their doctors at multiple clinics will take part. Doctors in some clinics will receive special communicatio…

This pilot study is testing whether two natural dietary supplements—taxifolin (found in apples and onions) and ergothioneine (found in mushrooms)—can improve immune function in healthy adults aged 50 to 65. Researchers will measure how well immune cells engulf and destroy threats…

This study looks at how four different FDA-approved flu vaccines affect the immune system in 50 adults aged 18-50 and 65-80. Researchers will measure antibody levels and memory B cells to see how age and past vaccination history influence the body's response. The goal is to under…

This study compares how well two FDA-approved COVID-19 vaccines—Novavax (a protein-based vaccine) and Pfizer (an mRNA vaccine)—trigger the immune system. Researchers will measure antibody levels against several virus variants in 54 healthy adults aged 18-79 who have risk factors …

This study follows 500 children under 18 who tested positive for flu, RSV, or COVID-19. Each child takes a daily nose swab for 14 days to measure how the virus levels change over time. Researchers also check if family members get sick. The goal is to understand when kids are most…

This study follows about 1,000 adults in the U.S. who test positive for COVID-19 or influenza. Participants fill out surveys about their symptoms and quality of life over six months. The goal is to understand how these illnesses affect daily activities and whether COVID-19 vaccin…

This study looks at whether eating a high-fiber diet (rich in fruits, vegetables, and whole grains) can change the bacteria in your gut and improve how well the flu vaccine works. Researchers will give 31 adults special meals and snacks before they get their flu shot. The main go…

This study looks at whether the bacteria in your gut and what you eat can influence how well the flu vaccine works. Researchers will collect blood and stool samples from 74 adults before and after they get their flu shot. The goal is to find links between gut microbiome diversity…

This study follows 1,500 healthy infants from birth to age 4 to understand how their first encounter with the flu—either through vaccination or natural infection—affects their immune system's response to later flu exposures. Pregnant mothers are enrolled before delivery, and thei…