INFLUENZA

This early-stage trial compares an experimental flu vaccine (H1ssF) with the standard seasonal flu shot (Flucelvax) in 112 adults aged 18-70. Some participants have had flu shots before, while others have never been vaccinated. The main goal is to check safety and how the immune …

This early-stage trial tests a new flu vaccine with an added ingredient (BK-01 adjuvant) to see if it is safe and triggers a strong immune response. About 160 adults aged 18 and older will receive either the new vaccine, a standard flu vaccine, or a placebo. Participants will be …

This study tests whether a new oral drug, TRX-100, can prevent flu infection in healthy adults aged 18-55. Participants will be exposed to the flu virus and monitored for symptoms and viral levels. The goal is to see if the drug is safe and effective at stopping the flu from taki…

This study tests whether adding corticosteroids to standard care can lower the risk of death in adults with severe flu pneumonia in the ICU. About 496 participants will receive either standard care alone or standard care plus different doses of steroids. The goal is to find a saf…

This study tests a new flu vaccine in 1200 adults aged 60 and older. Participants will receive either the new vaccine or a standard flu shot. Researchers will check how well the vaccine boosts immunity and monitor for any side effects over 30 days.

This study tests whether using two nasal protective devices together can lower the chance of getting respiratory infections like COVID-19 and the flu. About 2000 adults will use the devices in daily life for 8 weeks. The study also checks how easy they are to use and if they caus…

This study tests whether a new antiviral pill, onradivir, can help teenagers aged 12 to 17 recover faster from the flu. About 150 teens with uncomplicated influenza A will take either the medicine or a placebo once daily for five days. Researchers will track how quickly symptoms …

This study looks at how the brain works differently in people with smell problems caused by things like infections or injuries. Researchers will use brain scans, smell tests, and questionnaires to track changes over one year. 80 adults (including healthy volunteers) will take par…

This follow-up study looks at whether a supplement called TUDCA can help the flu vaccine work longer in adults aged 60-70. Participants from an earlier study will give one blood sample about 8 months after their flu shot to measure antibody levels and immune memory cells. No new …