Can mushroom and apple compounds boost your immune system?

NCT ID NCT05190432

Ongoing Knowledge-focused Sponsor: University of Southampton Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing whether two natural dietary supplements—taxifolin (found in apples and onions) and ergothioneine (found in mushrooms)—can improve immune function in healthy adults aged 50 to 65. Researchers will measure how well immune cells engulf and destroy threats. The goal is to understand if these compounds can help counter age-related immune decline.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Taxifolin (dihydroquercetin) and ergothioneine dietary supplements
What this could lead to: If successful, this study could point toward dietary strategies to support immune function in aging adults.
What could go wrong: This is a small, early pilot study in healthy volunteers, not designed to prove any health benefit. Results may not apply to the general population or lead to any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease common cold Inflammation inflammatory disease influenza

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING ANTIOXIDATIVE STRESS COLD INFLAMMATION INFLUENZA

Contacts and locations

Locations

NIHR Southampton Biomedical Research Centre

Southampton, Hampshire, SO16 6YD, United Kingdom

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