Could a Plant-Based vaccine beat the flu?

NCT ID NCT07291635

Ongoing ⭐️ VACCINE ⭐️ Sponsor: Aramis Biotechnologies Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 2 times

Summary

This study tests a new seasonal flu vaccine made from plants, called TVLP, in 728 adults aged 18 and older. The vaccine is compared to a standard flu shot to see if it is safe and triggers a strong immune response. The goal is to find the best dose for future development.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Plant-based seasonal flu vaccine (recombinant trivalent VLP)
What this could lead to: If successful, this could offer a new, plant-based option for seasonal flu vaccination, potentially faster to produce and more scalable than traditional egg-based vaccines.
What could go wrong: This is an early Phase 1/2 trial, so safety and immune response are still being tested. The vaccine may not work as well as existing flu shots, and side effects are unknown at this stage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

influenza

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLUENZA

Contacts and locations

Locations

CHU de Québec - Université Laval

Québec, Quebec, G1E 7G9, Canada
Canadian Center for Vaccinology (CCfV) - IWK Health

Halifax, Nova Scotia, B3K 6R8, Canada
Diex Recherche - Sherbrooke

Sherbrooke, Quebec, J1L 0H8, Canada
Diex Recherche - Trois-Rivières

Trois-Rivières, Quebec, G9A 4P3, Canada
Diex Recherche - Victoriaville

Victoriaville, Quebec, G6P 3Z8, Canada
Montreal Heart Institute

Montreal, Quebec, H1T 1C8, Canada
Vaccine Study Centre of McGill University Health Centre

Pierrefonds, Quebec, H9H 4Y6, Canada

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