FRAILTY

This study tests a 6-week program where nurses provide weekly phone calls and personalized advice to help frail older adults (65+) living at home. The goal is to reduce frailty and improve their ability to do daily activities. 100 participants will be split into two groups: one g…

This study tests a volunteer-led lifestyle program for older adults (60+) with sarcopenia, a condition causing muscle loss and weakness. The program includes workshops on nutrition and exercise, supported by nurses and trained volunteers. Researchers will measure changes in muscl…

This study tests a program called SHAPE that combines physical activity and nutrition advice for older adults after they leave the hospital for a severe flare-up of chronic lung disease. The goal is to reduce frailty and muscle loss, and improve recovery. About 90 participants wi…

This study will test whether silkworm pupa powder, taken daily for 12 weeks, can improve memory, daily living skills, and frailty in 100 people with mild-to-moderate Alzheimer's disease. Participants will take the powder twice a day and visit the clinic every 4 weeks for tests in…

This pilot study tests whether an 8-week program that mixes exercise with non-immersive virtual reality can improve balance, thinking, and daily activities in adults over 65. Sixty participants will be split into three groups: exercise plus VR, VR alone, or usual care. The goal i…

This pilot study tests a 24-week home exercise program called FITWISE for frail adults aged 60+. Caregivers help guide exercises using a video game-like system. Researchers will check if the program is practical and improves physical function. 60 participants will be split into t…

This study tests whether an 8-week tele-rehabilitation program can improve muscle mass, reduce frailty, and enhance quality of life in adults with cystic fibrosis. Participants will do supervised exercise sessions at home via video calls three times a week. The goal is to see if …

This pilot study will test a 12-week telehealth program for frail adults aged 65+ who have just left the hospital. The program includes weekly video sessions with exercise, self-management tips, and peer support, plus activity sensors to track movement. Researchers want to see if…

This study tests whether a digital prehabilitation app (HEAL-ME) combined with creatine and whey protein supplements can help maintain muscle health and reduce frailty in 100 adults with cirrhosis. Participants will use the app and take supplements for at least 3 months. The goal…

This study tests two different supervised exercise programs in 350 adults aged 60 and older in Angola. One program includes strength, balance, and coordination exercises, while the other focuses on basic strengthening and daily activities. Both are done three times a week for 12 …

This study tests a home strengthening program using the BandPass system—a Bluetooth exercise band and mobile app that gives real-time feedback. Researchers want to see if older adults (65+) can use it easily and if it improves their strength and mobility. Participants will do a 1…

This study tests whether a 10-week program combining strength exercises with muscle relaxation techniques can reduce frailty, anxiety, and burden in people caring for a loved one with Alzheimer's. About 62 caregivers will be randomly assigned to either the combined program or rel…

This study will test whether a virtual reality exercise program (PABLO) is better than traditional physiotherapy (Otago) at improving balance and reducing fall risk in adults aged 45 and older who have fallen before or have balance issues. About 80 participants will do either VR …

This study tests whether adding simple mental challenges—like counting or naming animals—to physical exercise helps frail adults over 65 improve their strength, balance, and thinking more than exercise alone. About 220 participants will be randomly assigned to either the dual-tas…

This trial tests whether a smartphone app can help people improve their fitness before cancer surgery. 60 adults scheduled for elective cancer surgery will either use the app or receive usual care. The app guides them through weekly walking tests, daily check-ins on exercise, nut…

This study will check if a score called EASIX, calculated from routine blood tests, can predict dangerous low blood pressure after anesthesia in frail patients having non-cardiac surgery. Researchers will monitor 160 frail patients' blood pressure closely after they receive anest…

This study follows 150 adults waiting for a kidney transplant to track how their physical and emotional health changes over time. Researchers will use a mobile app and interviews to measure frailty and quality of life. The goal is to identify patients who need extra support and i…

This study checks if a short questionnaire called G8 can correctly identify frailty in people aged 70 and older with solid tumors. Researchers will compare the G8 results with a full geriatric assessment in 150 patients. The goal is to see if the G8 tool works well for Portuguese…

This three-year study in 410 adults with congenital heart disease aims to see if AI-powered voice emotion detection can predict frailty and improve mental health. Participants will complete surveys and interviews, and some will receive AI-guided counselling. The goal is to better…

This study will compare 80 adults aged 40 and older—half living with HIV and half healthy—to see if those with HIV experience frailty, muscle loss, and cognitive decline earlier. Researchers will assess physical function, nutrition, and thinking skills. The goal is to understand …

This study looks at whether a health tracking platform can improve the health of elderly people who are frail. Over 1,000 seniors will use the platform for a year, and researchers will also figure out which health surveys best predict frailty. The goal is to find better ways to p…

This study looks at whether older adults with mild memory issues are more likely to become confused after planned hip replacement surgery. Researchers will test memory before surgery and watch for confusion in the first three days after. The goal is to see if a quick memory test …

This study tests whether a kidney transplant-specific comprehensive geriatric assessment (KT-CGA) can improve how older adults (60+) are evaluated for kidney transplants. Fifty participants will either receive the KT-CGA plus usual care or usual care alone. The goal is to see if …

This study will test a new way to offer vaccines to vulnerable patients—those with chronic diseases or weakened immune systems—during hospital visits. Researchers will see if offering, prescribing, and giving vaccines in the hospital increases how many people get vaccinated. The …

This study will follow 4,000 intensive care patients aged 80 and older to see how chronic and acute heart conditions impact their survival, daily function, and quality of life. Researchers will use simple tests to measure frailty and independence. The goal is to help doctors bett…

This study looks at whether an electronic comprehensive geriatric assessment (eCGA) can be used in primary care for adults aged 65 and older. Researchers will track frailty over 12 months and compare patient self-reports with doctor assessments. A smaller group will also try a pe…

This study looks at 100 elderly patients with hip fractures to see if quick, easy tests like muscle ultrasound, handgrip strength, and routine blood work can predict frailty. Frailty affects recovery after surgery, so finding a fast way to measure it could help doctors provide sa…

This study will check if a simple frailty score (ISAR) can predict medication problems in elderly patients visiting the emergency department. Researchers will review the medical records of 300 patients aged 75 and older, looking for inappropriate prescriptions and dangerous drug …

This study will check the health, nutrition, and daily living abilities of 330 older adults (age 60+) living in a rural village in Assiut, Egypt. Researchers will interview participants and take simple physical measurements like weight and blood pressure. No treatments are given—…

This study will follow 645 older adults (65+) who come to the hospital with a heart attack. Researchers want to see if frailty—a state of reduced strength and energy—affects how doctors treat them and whether they have serious problems like death or another heart event within 30 …

This study looks at 100 older women (60+) newly diagnosed with breast cancer to understand how frailty affects their quality of life. Researchers will use geriatric assessments and questionnaires to measure frailty and well-being over 6 months. The goal is to help doctors make be…

This study will enroll 850 adults over 65 who have had a heart attack (acute coronary syndrome). Researchers want to see if adding frailty measurements to standard risk scores improves the prediction of serious bleeding during the hospital stay and up to 6 months later. The goal …