FRAILTY

This pilot study is testing whether a 12-week telehealth support program can help frail older adults recover better after a hospital stay. The program provides weekly video sessions and uses activity sensors to encourage movement and monitor progress. Researchers will enroll 50 p…

This study is testing a special exercise program designed to help frail adults over 65 stay more functional and mentally sharp. The program combines physical and mental tasks and will be compared to usual care. Researchers will recruit 220 participants from primary care centers t…

This study tests whether a virtual reality exercise program is better than traditional physiotherapy at improving balance and preventing falls in adults aged 45 and older who have fallen before or have balance problems. Participants will do either VR-based exercises or standard b…

This study is testing whether a combination of a digital exercise and nutrition app, plus protein and creatine supplements, can help people with liver cirrhosis maintain their muscle strength and physical function. Researchers will enroll 100 adults with cirrhosis to use the app …

This study aims to see if two common dietary supplements, creatine and HMB, can boost the benefits of exercise for frail, older adults living in nursing homes. Eighty participants will follow a supervised exercise program for 12 weeks while taking either the supplements, a placeb…

This study aims to see if giving nutritional drinks to frail elderly patients before hip fracture surgery helps them recover better. Researchers will observe 228 patients aged 65+ to see if this support leads to fewer complications, shorter hospital stays, and lower risk of death…

This study is testing a home exercise system called BandPass, which includes a smart resistance band and a phone app, to see if it can help older adults maintain their strength and mobility. About 39 participants aged 65+ will use the system three times a week for 8 weeks to foll…

This study is testing a personalized digital program designed to help older adults living at home who are at risk of losing muscle strength (sarcopenia) and becoming frail. The program provides tailored exercise and nutrition plans through a digital platform, aiming to improve st…

This study is testing a new electronic health check-up tool for adults 65 and older to help doctors spot and track frailty during regular visits. It also includes a sub-study where some participants get a personalized exercise program designed by an expert to see if it can improv…

This study is testing whether a digital health tracking platform can help control and reduce frailty in older adults over one year. It will enroll 1,000 Medicare patients over age 65. Participants will be randomly assigned to either use the tracking platform or receive usual care…

This study aims to find the safer, more effective treatment for frail elderly patients with atrial fibrillation (AFib), a common heart rhythm problem that raises stroke risk. It will compare two approaches: a heart procedure (ablation) combined with a small plug to seal off a par…

This study aims to create and test a practical system for hospitals to offer and give recommended vaccines to adults with chronic diseases or weakened immune systems. It will involve 1,500 patients, offering vaccines during their hospital visits or stays. The goal is to see if th…

This study is testing a 10-week program combining strength training and relaxation techniques for people who care for a family member with Alzheimer's disease. It aims to see if this combination reduces physical frailty, anxiety, and the feeling of being overwhelmed better than r…

This study is testing whether a program run by nursing and exercise science students is practical and acceptable for improving frailty in older adults living in nursing homes. The 12-week program includes physical activity and other support. Researchers will measure if participan…

This study will test two different exercise programs to see which one better helps older adults stay strong, steady on their feet, and mentally well. Researchers will enroll 350 people aged 60 and older in Angola and randomly assign them to one of two 12-week exercise plans. The …

This study is testing whether adding whole-body vibration therapy to usual care helps improve muscle mass, strength, and physical function in older adults who are starting to become frail. It will compare two groups: one receiving vibration therapy plus usual care, and one receiv…

This study is testing if a phone app can help people scheduled for cancer surgery get stronger and feel less anxious before their operation. About 60 adults will use the app for weekly walking tests and daily check-ins on exercise, nutrition, and mood. Researchers will compare th…

This study aims to understand how existing and new heart problems affect the recovery and survival of very old patients in intensive care. Researchers will observe 4,000 patients aged 80 and older from hospitals worldwide, tracking their health for six months. The goal is to gath…

This study aims to find quick, objective ways to measure frailty in older adults (65+) who need surgery for a broken hip. Researchers will test if a simple muscle ultrasound, a handgrip strength test, and routine blood work can accurately predict a patient's frailty level. If suc…

This study aims to find out if a quick frailty screening tool used in the emergency room can identify which elderly patients are most likely to have unsafe or inappropriate prescriptions and dangerous drug interactions. Researchers will collect medical data from 300 patients aged…

This study aims to understand how frailty (physical weakness common in older age) influences treatment choices and short-term recovery in elderly patients who have had a heart attack. Researchers will follow 645 patients aged 65+ to see if adding a frailty assessment to standard …

This study aims to understand how frailty affects quality of life in older women with breast cancer. Researchers will follow 100 women aged 60+ in Egypt to see how their physical strength and well-being change over six months. The findings could help doctors create more personali…

This study aims to understand how aging affects people living with HIV compared to healthy individuals. Researchers will measure frailty, muscle loss, nutrition, thinking skills, and physical function in 80 adults aged 40 and older. The study is observational, meaning it collects…

This study aims to find better ways to predict who is most at risk of dying within 30 days after major abdominal surgery if they are 80 or older. Researchers will look back at the medical records of about 200 patients to see if measures of frailty (like a simple 5-point checklist…

This three-year study aims to understand how groups of symptoms relate to frailty in adults born with heart defects. Researchers will use artificial intelligence to analyze voice patterns for signs of emotion and test if counseling guided by this AI can improve mental health, fat…

This study aims to understand if a brief memory test given before hip replacement surgery can help predict which older patients might experience sudden confusion after their operation. Researchers will observe about 400 patients aged 65 and older across several hospitals in the C…

This study aims to understand the health needs of older adults living in a rural Egyptian village. Researchers will interview 330 people aged 60 and older about their health, diet, daily activities, and quality of life, and take basic measurements like weight and blood pressure. …

This study is testing a new, more detailed health check designed specifically for older adults being evaluated for a kidney transplant. Researchers want to see if adding this 45-60 minute check to the standard assessment is practical and acceptable for patients and doctors. The s…

This study aims to see if adding a measure of frailty (a state of reduced physical resilience) to standard risk scores can better predict serious bleeding in older patients hospitalized for a heart attack. It will enroll 850 patients over 65 years old. The goal is to gather knowl…