EPILEPSY

This early study is testing a new cell therapy for adults with severe epilepsy that doesn't respond to medications. Doctors will inject specially grown brain cells directly into the brain during surgery, and patients will take immune-suppressing drugs before and after. The main g…

This study is testing a smartphone app called EPIDAY that aims to predict the risk of an epileptic seizure. Adults with focal epilepsy will use the app daily to track warning symptoms. The goal is to see if a computer algorithm can use this information to reliably forecast high-r…

This study is testing whether a non-surgical, focused ultrasound treatment can safely reduce seizures in children whose epilepsy doesn't respond to medication. Researchers will follow 20 children for one year after the ultrasound treatment to see if it lowers seizure frequency an…

This study aims to find the right dose and check the safety of a liquid form of the seizure medicine zonisamide for children and teens with partial-onset seizures. It will enroll 40 participants, from 1 month to 17 years old, who are already on a stable seizure medication plan. R…

This study is testing whether a non-invasive brain training technique called neurofeedback can help reduce seizures in adults with epilepsy that doesn't respond to medication. Participants will use real-time brainwave feedback to try to learn to control their brain activity. The …

This study is testing a new type of brain scanner designed to more accurately find the specific area of the brain causing seizures in people with epilepsy. The goal is to improve planning for surgery that could control or cure seizures. Researchers will compare the new, more comp…

This study is testing whether adding therapy dogs to standard psychomotor therapy sessions can improve quality of life for adults with difficult-to-treat epilepsy. Researchers will enroll 76 adults who are already receiving therapy for emotional or movement challenges. They will …

This study is exploring if a brief, online therapy program can help improve the mental well-being of children and teenagers with epilepsy. It will test a combination of compassion-focused education and a loving-kindness meditation practice. Up to six young people, aged 12-17, wil…

This study aims to see if people with epilepsy have food or liquid left in their stomachs before surgery, even after following the usual fasting rules. Researchers will use a quick, painless ultrasound scan on the stomachs of about 30 adults with epilepsy who are scheduled for su…

This early-stage study aims to understand how an experimental drug called Cobenfy KarXT affects brain activity related to memory. Researchers will test 50 adults with epilepsy who are already in the hospital having brain monitoring for their seizures. Each participant will take t…

This study aims to see if a special educational session helps teenagers with epilepsy in Uganda understand their condition better. Researchers want to find out if this improved knowledge leads to better medication habits and less feeling of shame or stigma. The study will involve…

This study aims to understand the real-life challenges people with epilepsy face in school, at work, and in social situations. Researchers will ask 90 adults with epilepsy to complete surveys about their experiences with stigma and daily difficulties. The goal is to gather inform…

This study aims to find out if using virtual reality (VR) headsets increases the risk of seizures in teens and adults with epilepsy. Researchers will measure brain activity in 40 participants while they use a VR headset in different ways: with it off, with it on but no hand contr…

This study aims to understand how epilepsy affects people's daily lives and overall well-being. Researchers will ask 90 adults with epilepsy to complete a standard questionnaire about their quality of life during regular doctor visits. The goal is to learn more about the challeng…

This study is testing a new external brain device to see if it can detect specific brain signals that may predict epileptic seizures. Researchers will use the device to record brain activity and deliver targeted electrical stimulation in 8 patients with drug-resistant epilepsy wh…

This study aims to understand brain changes in adults with Dravet syndrome, a severe form of epilepsy with a high risk of sudden death. Researchers will use PET and MRI brain scans to compare 30 participants: 10 with Dravet syndrome, 10 with other drug-resistant epilepsy, and 10 …

This study aims to find out how common ADHD symptoms are in children who also have epilepsy. Researchers will follow 185 children to identify possible risk factors for developing ADHD in this group and see how it might affect their epilepsy. The goal is to gather knowledge to hel…

This study aims to see if watching a medical TV drama can improve people's knowledge about neurocysticercosis, a parasitic brain infection linked to epilepsy. Sixty young adults will be randomly assigned to either watch an episode of 'House M.D.' or not, and then take a quiz abou…

This study aims to identify early warning signs that a child's epilepsy won't respond to standard medications. Researchers will examine medical records, brain scans, and test results from 200 children with epilepsy. The goal is to help doctors spot resistant cases sooner and cons…

This study aims to better understand how the brain works during thinking, memory, and language, and how epilepsy affects these processes. Researchers will work with 38 patients who are already having surgery for hard-to-treat epilepsy, using new, tiny electrode grids placed on th…

This study aims to understand how drug-resistant epilepsy might change specific pathways in the brain that control breathing and sleep-wake cycles. Researchers will use advanced MRI and PET scans to compare brain activity and chemistry in 50 adults (some with epilepsy, some healt…