Brain-Computer interface aims to stop epileptic seizures before they start
NCT ID NCT06898138
First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times
Summary
This early study at Mayo Clinic tests a new implantable device called the Brain Interchange System in up to 8 people with drug-resistant epilepsy. The device records high-speed brain signals and can deliver targeted electrical stimulation to prevent seizures. Unlike current systems that react after a seizure starts, this one aims to detect warning signals and stop seizures before they happen. For now, the study only checks if the device works as intended, not whether it actually controls seizures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CorTec Brain Interchange System (implantable device for sensing and stimulation)
- What this could lead to
- If successful, this could pave the way for a future implant that stops seizures before they start, improving seizure control for people with drug-resistant epilepsy.
- What could go wrong
- This is a very early feasibility study with only 8 participants. It tests whether the device can detect and respond to brain signals, not whether it actually stops seizures. Many technical hurdles remain.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baylor College of Medicine
Houston, Texas, 77030-3498, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can mindfulness rewire the mind to lift depression in epilepsy?
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- Can invisible electric fields quiet the Brain's seizure signals?
- Can a new drug tame severe childhood epilepsy?