EPILEPSY
Clinical trials for EPILEPSY explained in plain language.
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Epilepsy drug study ends early: what we learned about Soticlestat's safety
Disease control TerminatedThis study looked at the long-term safety of soticlestat, an add-on seizure medicine, in children and adults with severe epilepsies like Dravet and Lennox-Gastaut syndromes. About 156 participants took the drug twice daily for as long as it helped them. The study was stopped earl…
Matched conditions: EPILEPSY
Phase: PHASE2 • Sponsor: Takeda • Aim: Disease control
Last updated May 17, 2026 00:29 UTC
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Brain implant study aims to cut seizures in epilepsy patients
Disease control TerminatedThis study tested a brain implant (deep brain stimulation) to reduce seizures in people with epilepsy that is not controlled by medication. 29 participants were followed for up to 3 years to see if the device safely lowers seizure frequency. The approach uses electrical pulses to…
Matched conditions: EPILEPSY
Phase: NA • Sponsor: MedtronicNeuro • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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Newborn seizure drug trial halted early
Symptom relief TerminatedThis study tested the drug lacosamide in newborns (up to 28 days old) who were still having seizures despite other treatments. The goal was to see if lacosamide could reduce seizure activity measured on brain wave tests. The trial was stopped early, and only 29 babies took part.
Matched conditions: EPILEPSY
Phase: PHASE2 • Sponsor: UCB Biopharma SRL • Aim: Symptom relief
Last updated May 11, 2026 20:48 UTC
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Blood protein may predict seizure return
Knowledge-focused TerminatedThis study looked at whether measuring a protein called S100B in the blood right after a first seizure can help predict if someone will have more seizures within a year. Researchers enrolled 37 adults who had their first seizure less than 24 hours earlier. The goal was to find a …
Matched conditions: EPILEPSY
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 17, 2026 00:31 UTC
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New implant tracks seizures for months without hospital stay
Knowledge-focused TerminatedThis study tested a small device placed under the scalp that records brain waves for up to 12 weeks in people with epilepsy. The goal was to see if it could detect seizures as well as standard hospital monitoring and patient diaries. The study involved 64 adults with seizures sta…
Matched conditions: EPILEPSY
Phase: NA • Sponsor: UNEEG Medical A/S • Aim: Knowledge-focused
Last updated May 17, 2026 00:24 UTC
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UK study examines Real-World impact of VNS therapy for epilepsy
Knowledge-focused TerminatedThis study looked at how vagus nerve stimulation (VNS) therapy affects hospital visits and daily life for people with drug-resistant epilepsy in the UK. Researchers reviewed medical records and asked patients about their experiences. The goal was to understand the real-world bene…
Matched conditions: EPILEPSY
Sponsor: LivaNova • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC
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Epilepsy patients try Self-Recorded brain tests at home
Knowledge-focused TerminatedThis study tested a new dry-electrode EEG headset that people with epilepsy could use at home to record their own brain activity. Researchers compared the quality of these home recordings to standard EEGs done in a clinic. The goal was to see if this simpler device could provide …
Matched conditions: EPILEPSY
Phase: NA • Sponsor: Karl Landsteiner Institute for Clinical Epilepsy Research and Cognitive Neurology • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC