EPILEPSY

This study tested a brain implant (deep brain stimulation) to reduce seizures in 29 adults with epilepsy whose seizures were not controlled by medication. Participants kept diaries to track seizure frequency over three years. The goal was to see if the device safely and effective…

This study looked at the long-term safety of soticlestat, an experimental drug, in children and adults with severe forms of epilepsy like Dravet syndrome and Lennox-Gastaut syndrome. Participants took soticlestat twice a day along with their usual seizure medicines. The study was…

This study tested the drug lacosamide in newborns with repeated seizures that were not controlled by standard medicines. The trial was small (29 babies) and was stopped early. Researchers compared lacosamide to usual care to see if it could reduce seizure time on brain monitoring…

This study followed 97 people with drug-resistant epilepsy in the UK who had a vagus nerve stimulation (VNS) device implanted. Researchers looked at medical records and patient surveys to see how the therapy affected hospital visits and seizures over time. The goal was to underst…

This study looked at whether measuring a protein called S100B in the blood right after a first seizure could help predict if someone will have more seizures within a year. The researchers planned to follow 37 adults for one year, but the study was stopped early. The goal was to f…

This study tested a new dry-electrode EEG headset that people with epilepsy can use at home to record their brain activity. Five adults with epilepsy first had a standard EEG in the clinic, then used the dry-electrode headset at home for 14 days. The goal was to see if the home r…

This study tested a new 3D scanner to measure how the brain shifts during surgery for epilepsy or tumor removal. Only one person took part before the study was stopped. The goal was to see if the scanner could accurately track brain surface changes over time, which could help sur…

This study tested a small device implanted under the scalp to record brain waves (EEG) continuously for up to 12 weeks in people with epilepsy. The goal was to see if it could detect seizures better than standard short-term hospital monitoring and patient diaries. The trial invol…