EPILEPSY

This study aimed to see if a medication called lacosamide could help control seizures in newborns when other standard medications weren't working well enough. It compared lacosamide against other standard anti-seizure drugs in babies under one month old. The trial was stopped ear…

This study aimed to check the long-term safety of an experimental drug called soticlestat when added to existing seizure medications. It involved 156 children and young adults with severe, hard-to-treat forms of epilepsy, including Dravet and Lennox-Gastaut syndromes. Participant…

This study tested a small, implanted EEG device designed to record brain activity continuously for 12 weeks in people with epilepsy. The goal was to see if this new device could accurately detect seizures compared to the standard method of video-EEG monitoring in a hospital. The …

This small, terminated pilot study explored whether people with epilepsy could use a new, dry-electrode EEG headset at home to record their brain activity. The goal was to see if home recordings were as useful for diagnosis as traditional, wet-electrode EEGs done by specialists i…

This study aimed to understand how a vagus nerve stimulation (VNS) device affects healthcare use and seizure control in people with severe epilepsy. Researchers looked at the medical records of 97 UK patients to compare hospital visits and seizure frequency for 12 months before a…

This study aimed to find out if measuring a protein called S100B in the blood right after a person's first seizure could help doctors predict if they would have more seizures in the next year. Researchers enrolled 37 adults who had just experienced their first seizure to track th…