COLON CANCER

This early-stage study tests a new cell therapy called KT032 in 24 people with advanced solid tumors (like ovarian, colon, or mesothelioma) that have spread to the belly lining. The main goal is to check safety and find the right dose. Participants must have tried standard treatm…

This study tests a drug called fruquintinib in 88 adults with advanced colon cancer that no longer responds to standard chemotherapies. The goal is to see if adding supportive care to manage side effects can help patients stay on treatment longer and slow cancer growth. It is a p…

This study tests if two immunotherapy drugs, cemiplimab and fianlimab, can safely shrink colon tumors before surgery in people with stage II-III colon cancer that hasn't spread. Participants get two IV doses, then surgery, and are followed for up to three years. The goal is to se…

This study tests a new drug combination (QL1706 plus XELOX) given before surgery for people with stage III colon cancer that is stable (pMMR/MSS). About 21 participants will receive four cycles of treatment, then have surgery. The main goal is to see if the cancer disappears comp…

This study aims to find certain antibodies in the blood of people with metastatic breast or colorectal cancer. These antibodies, which target a protein found in tumors, might also affect the heart and raise the risk of irregular heartbeats. Researchers will test blood samples fro…

This study looks at how a personalized strength training program affects people with different cancers (lung, colon, breast, lymphoma, and leukemia). 150 adults will either do supervised strength training plus home exercises, or just home exercises, for 12 weeks. Researchers will…

This study looks at where colon cancer spreads to lymph nodes in the small intestine's lining. About 406 adults with right-sided colon cancer will have their surgical tissue examined. The goal is to learn the exact pattern of spread so surgeons can remove the right amount of tiss…

This study looks at where colorectal cancer spreads to lymph nodes in 1200 patients. Researchers want to find patterns that could help doctors better plan treatment. Participants will have their removed lymph nodes analyzed and be followed for at least 5 years after surgery.

This study looks at whether a 6-month or 12-month follow-up colonoscopy is better for people who had a large colon polyp (20-50 mm) removed that was not cancerous. About 546 adults will be assigned to one of the two follow-up schedules. The goal is to see which timing finds any r…

This study looks at why some people who had surgery for colon cancer continue to have loose stools. Researchers will use a new device to check for bile acid problems and bacterial overgrowth in the small intestine. The goal is to better understand these symptoms and how they affe…