A simple breath test might spot multiple cancers before symptoms appear

NCT ID NCT07732686

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This trial is testing whether a breath analysis device can detect unique chemical patterns—called volatile organic compounds—that may signal the presence of cancer. Researchers will collect breath samples from 1,000 people with various cancers and 1,000 healthy volunteers, then use machine learning to see if the patterns can distinguish between cancer types and healthy breath. The goal is to develop a noninvasive, quick screening tool for early cancer detection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Proton Transfer Reaction Mass Spectrometry (PTR-MS) breath analysis
What this could lead to
If successful, this could lead to a noninvasive, low-cost breath test for early detection of several cancers, potentially improving survival rates.
What could go wrong
This is an early-stage study focused on collecting data and training algorithms. The breath test may not be accurate enough for real-world screening, and results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • OU Health Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73117, United States

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