Immunotherapy duo aims to shrink colon tumors before surgery

NCT ID NCT07224022

First seen Nov 03, 2025 · Last updated Apr 28, 2026 · Updated 31 times

Summary

This study tests whether two immunotherapy drugs, cemiplimab and fianlimab, can safely shrink colon tumors before surgery in people with stage II-III colon cancer that hasn't spread. Participants get two IV doses, then surgery, and are followed for up to three years. The goal is to see if this approach is feasible and safe, and to measure how well it controls the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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