COGNITIVE DECLINE

This small, early-stage study tested whether drinking beetroot juice could improve blood flow to the brain and reduce artery stiffness in adults aged 50-79. Sixteen participants were randomly assigned to drink either regular beetroot juice or a version with the key ingredient rem…

This study tested whether a culturally adapted 'brain healthy' soul food diet was practical and acceptable for older African Americans. The 29 participants followed the diet for 12 weeks, attending cooking classes and receiving coaching calls. Researchers measured changes in weig…

This study tested a new digital tool that scans patients' electronic health records to find older adults who might have undetected memory problems or be at risk for Alzheimer's disease. Researchers wanted to see if the tool was practical to use in primary care clinics and if send…

This study tested whether a new blood test for Alzheimer's disease helps doctors make better decisions. Researchers had 178 neurologists review simulated patient cases to see if having the test results changed their recommendations for follow-up tests and treatments. The goal was…

This study tested whether a new blood test could accurately diagnose Alzheimer's disease. Researchers compared blood samples from 200 people—some with Alzheimer's and some healthy—over two years. They measured two specific protein changes in the blood to see if they could reliabl…

This study tested whether a 24-week home-based program of physical activity and brain training could prevent or delay memory loss in older women with heart disease. Researchers enrolled 253 women aged 65 and older who were at high risk for memory decline. They compared different …

This study tested a lifestyle program called 'Fit Mind' to see if it could lower factors linked to Alzheimer's disease risk in older adults. The 8-session program included brain games, physical activity, nutrition tips, and social activities. Researchers compared changes in risk …

This study tested whether daily supplements made from chicken extract could help prevent cognitive decline in older adults who were not yet diagnosed with dementia. Over two years, 276 participants aged 55-75 either took the supplement, a related peptide, or a placebo. Researcher…

This study tested a culturally tailored health promotion program, led by a community health worker, to see if it could help prevent memory and thinking problems in Latino adults aged 50 and older who are living with HIV. The program aimed to improve overall health through activit…

This study tested whether ramipril, a common blood pressure medication, could help prevent memory loss and thinking problems in people with glioblastoma (an aggressive brain cancer) who receive radiation and chemotherapy. Seventy-five participants took ramipril daily during their…

This study tested whether a daily mushroom supplement in gummy form could help improve memory, focus, and mood in adults. Over 8 weeks, 35 participants took the gummies and completed memory tests and questionnaires. The goal was to see if the supplement could ease common symptoms…

This study tested whether a noninvasive brain stimulation technique could improve memory in people with mild cognitive impairment (MCI), an early stage of memory loss. 69 participants were randomly assigned to receive either active stimulation to one of two brain areas or a place…

This study tested whether starting brain training exercises early during a hospital stay could help older adults (65+) recover their thinking skills after experiencing sudden, severe confusion (delirium). 283 patients were randomly assigned to receive either the special cognitive…

This small, completed pilot study tested whether two different types of computerized brain training programs, both paired with light physical activity, could help improve thinking skills like memory and attention in people with multiple sclerosis (MS). Participants used either a …

This study aimed to understand how temporary pain affects a person's ability to learn and remember new walking patterns, especially in older adults. Researchers tested 61 healthy young and older adults, using mild electrical stimulation to create brief pain during a walking task.…

This study aimed to understand how a non-invasive light therapy, called transcranial photobiomodulation, affects brain blood vessel health and cognitive function like memory and thinking. It involved 24 adults aged 18-80 who received up to eight light therapy sessions over four w…

This study tested whether a short, 6-game brain exercise on a tablet is practical to use in busy pre-surgery areas. Researchers wanted to see if a patient's score on these games could help predict their risk of developing delirium (a state of sudden confusion) after a major opera…

This research project explored whether getting fitter through a home-based high-intensity exercise program could help older adults maintain their language abilities, like word-finding and sentence comprehension. It compared these potential benefits between people who speak one la…

This small, completed study aimed to see if drinking a Keto5 XOGenius beverage daily could improve markers linked to heart and brain health. It involved 6 healthy adults aged 18-50. Researchers measured things like blood pressure, cholesterol, blood vessel function, and cognitive…

This study aimed to understand if regular exercise can improve memory and mood in healthy middle-aged adults, and whether changes in gut bacteria play a role. 52 participants, aged 45-65 who did not exercise regularly, were assigned to either a 12-week group exercise program or a…

This study aimed to collect baseline information on normal brain function from healthy adults aged 50 and older. Researchers used a digital cognitive testing tool called BrainCheck to measure memory, attention, and other thinking skills in 1300 participants. The goal was to creat…