COGNITIVE DECLINE

This study looked at whether a blood test can help diagnose Alzheimer's disease. Researchers measured two specific proteins in the blood of 200 people (some with Alzheimer's, some healthy) to see if the test could tell the difference. The goal is to create a simpler, less invasiv…

This study tested whether an 8-week course taught by a robot could help prevent or delay cognitive decline in older adults with mild memory problems. 80 people aged 65 and older took part, with half attending robot-led classes and the other half receiving no intervention. The pro…

This study tested a health program designed for older Latino adults living with HIV to see if it could help prevent cognitive decline (memory and thinking problems). Thirty participants completed the program, which focused on healthy habits and cultural relevance. The main goal w…

This study tested a 4-week program called Zinde Zihin ("Fit Mind") in 62 older adults living in nursing homes. The program included brain games, exercise, nutrition advice, and stress management. Researchers measured changes in Alzheimer's risk scores and found that the program m…

This study looked at whether a home-based physical activity program and computer-based cognitive training, alone or together, could prevent memory loss in older women with heart disease. 253 women aged 65 and older with cardiovascular disease but no regular exercise or cognitive …

This study tested whether a daily chicken extract and peptide supplement could prevent or slow cognitive decline in older adults without dementia. Over 2 years, 276 participants aged 55-75 with normal cognition or mild memory issues took either the supplement or a placebo. The st…

This study tested whether Auri Super Mushroom Daily Gummies can help with focus, memory, and energy in 35 adults aged 30 and older who reported forgetfulness, low focus, low energy, and low mood. Participants took two gummies daily for 8 weeks and completed memory and attention t…

This pilot study tested two different computer-based brain training programs that also include light physical activity. The goal was to see if they could help improve thinking skills like memory and attention in people with multiple sclerosis (MS). The study planned to enroll 40 …

This study tested a special exercise program that combines turning movements with thinking tasks to help people with diabetic nerve damage. Fifty adults aged 50 and older with mild balance and thinking problems took part. The goal was to see if this training could improve their b…

This study tested whether the blood pressure medication Ramipril could help prevent memory loss in people with glioblastoma (a type of brain cancer) who are receiving radiation and chemotherapy. 75 participants took Ramipril during and for four months after their cancer treatment…

This study tested whether a noninvasive brain stimulation technique called repetitive Transcranial Magnetic Stimulation (rTMS) could improve memory in people with mild cognitive impairment (MCI). 69 participants were randomly assigned to receive active rTMS to one of two brain ar…

This study tested whether a natural supplement called Brain Blossom can improve memory and thinking skills in adults aged 50 to 70. Sixty participants took either the supplement or a placebo for 8 weeks. Researchers measured changes in cognitive test scores and self-reported memo…

This study tested whether digital or physical brain games can improve thinking, mood, and quality of life in 514 older adults with mild-to-moderate Alzheimer's disease. Participants did one-on-one cognitive stimulation activities, either on a computer or with traditional material…

This study tested whether a virtual reality program that shows nostalgic scenes (like old neighborhoods or festivals) could improve emotional well-being and thinking skills in older adults with mild memory problems. Sixty-four people aged 65 and older took part, using VR twice a …

This study tested a live-streaming group program called Brain Health Together for older adults with mild cognitive decline. The program aimed to help participants improve brain health through lifestyle changes. 208 people took part, and the researchers measured changes in thinkin…

This study looked at whether older African Americans (55+) with heart disease risk factors could follow a special diet called MIND+SOUL. The diet combines brain-healthy foods with soul food traditions. Researchers measured how many people stuck with the diet and checked changes i…

This study looked at how short-term pain impacts the ability to learn and remember new walking patterns in 61 healthy young (18-35) and older (55-85) adults. Researchers measured how well participants learned and retained a new way of walking while experiencing pain, and compared…

This study looked at whether giving doctors the results of a new Alzheimer's blood test helps them make better decisions. 178 neurologists and dementia specialists in the US took part in virtual patient simulations. The goal was to see if the test results changed how they diagnos…

This study looked at whether regular exercise and being bilingual can help older adults maintain their language and thinking skills. Over 200 healthy older adults took part, with some doing a home-based high-intensity workout program. The goal was to measure changes in fitness, l…

This study tested whether a gentle electrical current applied to the scalp at a specific frequency (40 Hz) could strengthen brain waves linked to memory in 30 healthy adults aged 50-80. Participants performed a memory task while receiving stimulation to different brain areas. The…

This pilot study tested whether combining lifestyle changes, risk factor management, medications, and supplements could improve movement, thinking, and immune health in adults aged 50-70. The main goal was to see if the approach was feasible, not to prove it works. Only 23 people…

This study tested whether starting cognitive training early in the hospital and continuing it at home for 12 weeks could improve thinking and memory in older adults (65+) who experienced delirium. A total of 283 participants were randomly assigned to receive the cognitive interve…

This study collected thinking and memory test results from 1,300 healthy adults aged 50 and older. The goal was to create a standard reference of what normal cognitive function looks like in this age group. Researchers also checked whether the test scores were consistent when rep…

This study looked at whether older adults (60+) scheduled for major surgery can play a short set of brain-training games on a tablet before their operation. The goal was to see if their first-time game scores could help predict who might experience confusion (delirium) after surg…

This early-phase study looked at whether drinking beetroot juice (rich in natural nitrates) could improve artery stiffness and brain blood flow in adults aged 50-79. Sixteen participants were randomly given either nitrate-rich or nitrate-free beetroot juice. The goal was to see i…

This study tested whether a computer tool that scans electronic health records can identify older adults (65+) who may have undetected mild cognitive impairment or Alzheimer's disease. Researchers then used patient-friendly messages to encourage these individuals to get a cogniti…

This small study looked at whether drinking a KETO5 XOGenius beverage daily could improve markers of heart and brain health in 6 healthy adults aged 18-50. Researchers measured blood pressure, cholesterol, artery stiffness, and cognitive function. The goal was to gather initial d…

This study looked at how exercise affects memory and the gut microbiome in healthy adults aged 45-65 who were not very active. Researchers measured changes in memory tasks and gut bacteria from stool samples. The goal was to understand the link between physical activity, brain fu…

This study looked at whether shining a special light on the head (called transcranial photobiomodulation) can improve blood flow in the brain and help with thinking skills. Researchers tested 24 adults aged 18 to 80. The goal was to see if this light therapy could be a simple way…