Exercise may sharpen memory and reshape gut bugs in midlife

NCT ID NCT05397990

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether 12 weeks of moderate exercise, three times a week, can improve memory and change gut bacteria in healthy adults aged 45 to 65. Researchers measured memory tasks and analyzed stool samples. The goal was to understand how exercise might help keep the brain healthy during middle age.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If results show exercise improves memory and gut health, it could support using physical activity to protect brain function as we age.
What could go wrong
This is a small, completed observational study with only 52 participants. Findings may not apply to everyone, and it does not test a treatment or cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COGNITIVE DECLINE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Curie Kim

    London, London, SE5 8AZ, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.