AORTIC VALVE STENOSIS
Clinical trials for AORTIC VALVE STENOSIS explained in plain language.
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New blood thinner combo may be safer after valve replacement
Disease control CompletedThis study tested whether a single blood thinner (ticagrelor) is safer than the standard two-drug combination after a minimally invasive heart valve replacement (TAVI) for aortic stenosis. 50 older adults participated, and researchers tracked complications like bleeding, stroke, …
Matched conditions: AORTIC VALVE STENOSIS
Phase: PHASE3 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated May 17, 2026 11:47 UTC
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New heart valves show promise for indian patients with severe aortic stenosis
Disease control CompletedThis study tested two new heart valves (Portico and Navitor) in 30 Indian patients with severe aortic stenosis, a condition where the heart's main valve becomes narrow. The goal was to see if the valves were safe and worked well. Patients were followed for 9 months to check for c…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 17, 2026 11:39 UTC
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Heart valve procedure may be safer without Pre-Stretching
Disease control CompletedThis study looked at 250 people with severe aortic stenosis who needed a new heart valve placed through a tube in an artery (TAVI). The researchers compared doing the procedure with or without first stretching the old valve with a balloon. They wanted to see if skipping the ballo…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Disease control
Last updated May 17, 2026 11:33 UTC
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New heart valve shows promise in large study
Disease control CompletedThis study tested a new heart valve called Evolut PRO in 638 people with a narrowed aortic valve (aortic stenosis). The valve was implanted using a less invasive procedure. The study found that 30 days after the procedure, the death rate was low and met the safety goal. The valve…
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: Medtronic Cardiovascular • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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Nerve block eases pain during heart valve procedure, study finds
Symptom relief CompletedThis study tested whether an ultrasound-guided TAP block (a type of nerve block) can reduce pain and improve stability during a heart valve replacement procedure called TAVI. Fifty adults undergoing elective TAVI received either the block or standard care. The goal was to see if …
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Nerve block may ease pain during heart valve replacement
Symptom relief CompletedThis study looked at whether a special ultrasound-guided nerve block (PENG block) can help control pain and reduce the need for extra pain medicine in 40 adults undergoing a minimally invasive heart valve replacement called TAVI. The block numbs nerves around the hip area. Resear…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Medipol University • Aim: Symptom relief
Last updated May 11, 2026 20:48 UTC
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Heart stiffness measured during surgery to understand aortic stenosis
Knowledge-focused CompletedThis study measured how stiff the heart muscle is during planned aortic valve replacement surgery for aortic stenosis. Researchers compared stiffness in 98 patients with aortic stenosis to a reference group having bypass surgery. The goal was to see if the extra pressure from aor…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated May 17, 2026 11:36 UTC
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Heart imaging breakthrough may sharpen TAVI predictions
Knowledge-focused CompletedThis study tested whether two advanced heart ultrasound techniques (LACI and LV speckle tracking) can better predict complications like hospital readmission, heart attack, or stroke after TAVI valve replacement. Researchers studied 100 patients with severe aortic stenosis before …
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: Damanhour University • Aim: Knowledge-focused
Last updated May 17, 2026 11:35 UTC
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Heart scarring secrets revealed in aortic stenosis study
Knowledge-focused CompletedThis study examined 22 patients with severe aortic stenosis who were scheduled for valve surgery. Before surgery, they had an ultrasound of the heart, and during surgery a tiny sample of heart muscle was taken to check for scarring. The goal was to see if ultrasound measurements …
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: Norwegian University of Science and Technology • Aim: Knowledge-focused
Last updated May 17, 2026 11:33 UTC
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MRI scans reveal heart muscle healing after valve surgery
Knowledge-focused CompletedThis study looked at 86 people with severe aortic valve stenosis who had valve replacement surgery. Researchers used special MRI scans to measure scarring in the heart muscle before and one year after surgery. The goal was to see if the heart muscle heals after the valve is repla…
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Heart surgery showdown: does a gentler machine protect tiny blood vessels?
Knowledge-focused CompletedThis study looked at 60 heart surgery patients to see how two types of heart-lung machines affect blood flow in the smallest blood vessels. One method was a newer, less invasive approach, and the other was the standard method. The goal was simply to observe and compare, not to pr…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Aristotle University Of Thessaloniki • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
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New study tests digital tool to cut heart valve surgery wait times
Knowledge-focused CompletedThis study tested a program that combines a patient app with hospital coordination to see if it can shorten the time to get a TAVI procedure for aortic stenosis. Over 800 adults with severe aortic valve narrowing took part. The goal was to see if more patients could get treated w…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
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Computer alerts may help close gaps in heart valve care
Knowledge-focused CompletedThis study tested whether automated alerts sent to doctors through electronic health records could improve care for patients with severe aortic stenosis or mitral regurgitation. Over 2,100 patients were included, and the study compared outcomes between clinics that received alert…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Tempus AI • Aim: Knowledge-focused
Last updated May 06, 2026 16:04 UTC