Heart surgery anesthesia showdown: sevoflurane vs propofol
NCT ID NCT02851433
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether the anesthetic sevoflurane protects the heart better than propofol during aortic valve replacement surgery. 82 patients were randomly assigned to receive either sevoflurane or propofol during and after surgery. The researchers measured troponin levels, a marker of heart stress, to see which anesthetic caused less damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sevoflurane (inhaled anesthetic) and Propofol (intravenous anesthetic)
What this could lead to
If sevoflurane proves better at protecting the heart during surgery, it could become the preferred anesthetic for valve replacement, reducing heart damage.
What could go wrong
This is a small, completed Phase 4 trial with only 82 participants, so results may not apply to all patients. The benefit is measured by a lab marker (troponin), not long-term outcomes.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CHU Dijon Bourgogne
Dijon, 21079, France