New device catches debris during heart valve procedure to protect the brain

NCT ID NCT07627984

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a device designed to catch and remove debris that can break loose during transcatheter aortic valve replacement (TAVR), a procedure to replace a narrowed heart valve. The device uses two filters placed in arteries leading to the brain. The trial involved 260 people and measured brain lesions on MRI scans after the procedure. The goal was to see if the device reduces brain injury and improves safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cerebral embolic protection device

What this could lead to

If it works, this device could make TAVR safer by reducing the risk of brain damage from debris during the procedure.

What could go wrong

This is a completed trial with 260 participants, but the device only protects certain brain areas and may not prevent all complications. It is not a treatment for the underlying heart disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Xiamen Cardiovascular Hospital Xiamen University

    Xiamen, China