AORTIC VALVE STENOSIS
Clinical trials for AORTIC VALVE STENOSIS explained in plain language.
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Experimental valve treatment tested in just one patient
Disease control TerminatedThis study tested a device called Leaflex Performer for people with severe aortic stenosis who could not have standard valve replacement. Only one person took part before the study was stopped. The goal was to see if the device was safe and could improve valve function.
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Pi-cardia • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New Heart-Slicing procedure tested in tiny study
Disease control TerminatedThis study tested a new procedure called SESAME that uses a special wire to slice away extra tissue from the heart wall in people with a condition that blocks blood flow. Only one adult took part before the study was stopped early. The goal was to see if the procedure could be do…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated May 08, 2026 12:04 UTC
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Massive registry aims to guide aortic valve care
Knowledge-focused TerminatedThis study was a large registry that planned to follow 180,000 patients in Germany with aortic valve problems (narrowing or leaking). Its goal was to compare newer, less invasive treatments like TAVI with standard open-heart surgery to see which works best and for whom. The regis…
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: German Aortic Valve Registry • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC