AORTIC VALVE STENOSIS
Clinical trials for AORTIC VALVE STENOSIS explained in plain language.
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Can a single stitch beat a double closure for TAVI patients?
Disease control Not yet recruitingThis trial compares two methods for closing the main artery in the leg after a TAVI procedure, which replaces a heart valve without open surgery. Half of the participants will have the artery closed with a single suture device, while the other half will receive a hybrid approach …
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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A new heart valve without Open-Heart surgery: can it help High-Risk patients?
Disease control Not yet recruitingThis trial is testing a new device called the Crea Aortic Valve, a replacement heart valve that can be implanted through a catheter without open-heart surgery. It is designed for people aged 60 and older with severe aortic stenosis—a narrowing of the heart's main valve—who are co…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Onecrea Medical Inc. • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Could a heart pill delay valve replacement?
Disease control Not yet recruitingThis study tests whether the drug vericiguat can slow the buildup of calcium on the aortic valve in people with mild-to-moderate aortic valve stenosis. Participants take vericiguat or a placebo daily for 24 months, with regular heart scans to track valve calcium and function. The…
Matched conditions: AORTIC VALVE STENOSIS
Phase: PHASE2 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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Gentle second chance: new Valve-in-Valve study for failing heart valves
Disease control Not yet recruitingThis study follows about 300 patients across Europe who need a second minimally invasive heart valve replacement (TAVI-in-TAVI) because their first valve has worn out or is leaking. Doctors will use the Myval valve for the replacement. The study will track how well the procedure …
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: IHF GmbH - Institut für Herzinfarktforschung • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Could a simple antibiotic combo save lives after heart valve surgery?
Disease control Not yet recruitingThis study will test whether giving an extra antibiotic during a heart valve replacement procedure (TAVI) can lower the chance of bloodstream infection or death within 6 months. About 2,000 patients in Denmark will take part. Half will get the standard antibiotic, and half will g…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Rigshospitalet, Denmark • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Smaller incision, faster recovery? new study tests heart valve surgery approaches
Symptom relief Not yet recruitingThis study compares two types of heart valve surgery: a newer, less invasive method through a small cut on the right side of the chest versus the traditional method through a cut down the middle of the chest. Researchers will measure how quickly patients recover, including time o…
Matched conditions: AORTIC VALVE STENOSIS
Phase: NA • Sponsor: Chaudhry Pervaiz Elahi Institute of Cardiology • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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Heart valve unit may cut brain fog after procedure, study hopes
Knowledge-focused Not yet recruitingThis study will follow 500 people with severe aortic stenosis who need a heart valve replacement. Researchers want to see if a dedicated Heart Valve Unit—a team of heart specialists working together—can reduce confusion, delirium, and memory problems that sometimes happen after t…
Matched conditions: AORTIC VALVE STENOSIS
Sponsor: Heart and Brain Research Group, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC