Synovium disorder

Rheumatoid arthritis and gout can look alike, making them hard to tell apart early. This study will use ultrasound to see if it can reliably distinguish between the two conditions. Researchers will examine 100 adults with suspected or confirmed arthritis, scoring joint inflammati…

This study tests whether a new medicine called Fexuprazan (Fexuclue) can prevent stomach ulcers caused by NSAID painkillers like ibuprofen. About 360 adults with joint or muscle pain who need daily NSAIDs will take either Fexuprazan or an older drug (Lansoprazole) for 24 weeks. T…

This study tests if deltoid strengthening exercises can reduce pain and improve movement in people with frozen shoulder (adhesive capsulitis). 48 adults aged 40-60 with stage II or III frozen shoulder will do specific isometric exercises targeting the deltoid muscle. Researchers …

This study tests whether adding Osteopathic Manipulative Treatment (OMT) — a non-invasive, hands-on therapy — to standard care helps people with frozen shoulder recover faster and feel more satisfied. About 300 adults who have not yet been treated for frozen shoulder will be assi…

This study compares 3D-printed hand orthoses (braces) to traditional custom-made ones in 100 adults with chronic hand conditions from nerve, muscle, or bone issues. The goal is to see if the 3D-printed versions work just as well for daily activities, are more satisfying, and cost…

This study tests a new type of nerve block (PENG block) for people with chronic shoulder pain that hasn't improved with other treatments. 45 adults will get an ultrasound-guided injection of numbing medicine and steroid. Researchers will measure pain, shoulder function, and satis…

This study looks at whether using a home-based electrical stimulation device, along with standard physical therapy, can help reduce pain and improve shoulder function in people with frozen shoulder. Ten adults diagnosed with the condition will use the device at home while continu…

This study tests whether cross training—exercising the healthy arm—can improve pain, function, and mobility in people with frozen shoulder, without directly working the painful shoulder. About 38 adults aged 18-65 with unilateral frozen shoulder will be randomly assigned to stand…

This study compares two common treatments for frozen shoulder (adhesive capsulitis): a procedure that stretches the shoulder joint capsule (capsular distension) and a steroid injection. Both are followed by a rehab program. The trial will measure pain, movement, and disability in…

This study tests whether a robotic arm exoskeleton can help people with frozen shoulder move better and feel less pain. About 40 adults with stiff-phase frozen shoulder will use the robot for assisted exercises. The goal is to see if the robot improves shoulder range of motion an…

This study tests whether a long-acting painkiller (bupivacaine-meloxicam) can reduce pain and the need for opioid medications after robot-assisted knee replacement. 150 adults with knee osteoarthritis will receive either the new painkiller or a standard injection. Researchers wil…

This study looks at whether adding neck and upper back mobility exercises to standard care can improve posture, reduce shoulder pain, and increase range of motion in people with frozen shoulder. Researchers will enroll 40 adults aged 20 to 70 who have been diagnosed with frozen s…

This early-phase trial will test four orthobiologic treatments—PRP, bone marrow concentrate, hyaluronic acid, and nanofat—in 300 adults with various muscle, joint, tendon, or bone conditions. The goal is to see if these natural substances can reduce pain and improve joint functio…

This study tests whether a home-based virtual reality (VR) exercise program is practical and helpful for people with shoulder pain lasting more than three months. Thirty adults aged 16 and older with rotator cuff syndrome, frozen shoulder, or shoulder instability will use a VR he…

Frozen shoulder causes pain and stiffness. A common treatment called hydrodistension injects fluid into the shoulder joint to stretch it, but it can be painful. This study tests whether giving a nerve block first can reduce that pain and improve results. Fifty adults with frozen …

This study tests whether combining two manual therapy techniques—Mulligan mobilization and scapular mobilization—can improve shoulder movement and reduce pain in people with frozen shoulder better than standard physiotherapy. Thirty-eight adults aged 30 to 60 with unilateral froz…

This study explores whether a non-invasive treatment called extracorporeal shock wave therapy (ESWT) can reduce pain and improve shoulder movement in people with chronic adhesive capsulitis (frozen shoulder) who haven't gotten better with standard physiotherapy. Researchers will …

This study tests three ways to inject medicine into the shoulder joint for people with frozen shoulder (adhesive capsulitis). Thirty adults with shoulder pain and stiffness will receive a steroid and numbing injection through the front, back, or both. The goal is to see which met…

This study looks at whether a mobile app can help people with common pains (neck, shoulder, back, or knee) do their prescribed home exercises more regularly. About 30 adults will be split into two groups: one using the app and one doing traditional exercises. The goal is to see i…

This study looks at whether adding nerve-stretching exercises to standard capsule-stretching exercises can improve shoulder movement in people with frozen shoulder (adhesive capsulitis). About 50 adults aged 40–70 with moderate-to-severe frozen shoulder will be split into two gro…

This study tests whether adding pectoralis minor stretching and strengthening to standard mobility and stability exercises can better reduce shoulder pain and improve movement in people with frozen shoulder (adhesive capsulitis). About 70 adults aged 40-70 will be randomly assign…

This study tests whether low-level laser therapy or muscle energy techniques work better for reducing pain and improving shoulder movement in people with type 2 diabetes who have frozen shoulder. Thirty-six adults aged 18 to 65 will receive one of the two treatments plus standard…

This study tests whether a personalized exercise program based on muscle structure works better than a standard eccentric heel-drop program for people with chronic Achilles tendinopathy. Twenty adults with mid-tendon pain for at least 3 months will be randomly assigned to one of …

This study tests whether adding fascial therapy (a type of hands-on tissue manipulation) to standard electrotherapy can improve pain, movement, and joint awareness in people with frozen shoulder. Thirty-six adults aged 35-60 will be split into two groups: one gets only electrothe…

This study will test whether adding exercise training to standard electrotherapy (heat, TENS, ultrasound) helps people with frozen shoulder (adhesive capsulitis) more than electrotherapy alone. Thirty-two adults aged 35-60 will be split into two groups and treated for 3 weeks. Re…

This study aims to translate and adapt a widely used questionnaire for musculoskeletal problems into Urdu. Researchers will enroll 110 Urdu-speaking adults, including patients with muscle or joint issues and healthy volunteers. The goal is to create a validated tool to measure sy…

This study will explore if menopause and blood sugar levels are linked to frozen shoulder in women. Researchers will survey women who have had frozen shoulder and closely monitor a smaller group of perimenopausal women with and without the condition. The goal is to understand why…

This study looks at how patients feel when reading their own medical notes. Some will read the original doctor's note, others will read a simpler version written by artificial intelligence. Researchers want to see if the AI summary changes how much patients trust their doctor or …

This study looks at whether analyzing synovial tissue can help doctors better manage pigmented villonodular synovitis (PVNS), a rare joint disease that causes pain and joint damage. Researchers will collect tissue samples from 30 patients through biopsy or surgery to assess quali…

This study tests a decision support system called SmaRTWork to help people on sick leave due to muscle or back pain return to work. About 298 adults in Norway will either use the system or receive usual care. The main goal is to see if the tool helps them return to work sustainab…

This study will test a system called AuReha to see how well it measures arm movement precision in people with shoulder issues like instability or stiffness. About 52 adults will do exercises with both their healthy and affected arms, and the system will track movement accuracy, t…