Hormone therapy may thaw frozen shoulders faster — a trial puts it to the test

NCT ID NCT07736027

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial tests whether adding hormone replacement therapy (HRT) to a standard physiotherapy program improves pain, movement, and function in postmenopausal women with frozen shoulder. Fifty-six women aged 40 to 60 with stage I or II frozen shoulder will receive 12 weeks of supervised physical therapy, with half also taking HRT. The study aims to see if HRT can boost recovery and help personalize treatment for this common condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
hormone replacement therapy (HRT) combined with a standardized physiotherapy program
What this could lead to
If HRT enhances recovery, it could point toward a more effective treatment approach for frozen shoulder in postmenopausal women.
What could go wrong
This is a small, early-stage trial with 56 participants. HRT carries known risks, and any added benefit over physiotherapy alone may be modest or absent.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centro Reformer Pilates Center

    Istanbul, Kadikoy, 34710, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.