Joint tissue study aims to personalize rare disease treatment

NCT ID NCT07503821

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether analyzing synovial tissue can help doctors better manage pigmented villonodular synovitis (PVNS), a rare joint disease that causes pain and joint damage. Researchers will collect tissue samples from 30 patients through biopsy or surgery to assess quality and patient acceptance. The goal is to understand the disease better and see if tissue analysis can guide personalized treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to better, personalized treatment plans for people with PVNS, potentially reducing pain and joint damage.

What could go wrong

This is a small, early-stage study focused on gathering information, not testing a treatment. It may not lead to immediate changes in patient care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

synovitis tenosynovial giant cell tumor, diffuse type

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Nantes

    Nantes, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospices Civils de Lyon

    Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Cochin APHP

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact