Polyp of large intestine

This study tests whether adding a heat treatment (thermal ablation) to the standard procedure for removing large colon polyps can lower the chance they grow back. About 752 adults will be randomly assigned to receive either standard removal alone or standard removal plus burning …

This trial compares two endoscopic techniques for removing flat, non-cancerous colorectal polyps that are 10-20 mm in size. One method uses a cold snare (no heat), while the other uses a hot snare with electrocautery. The goal is to see if the cold approach is just as effective a…

This trial compares two techniques—snare tip soft coagulation and hybrid APC—used to burn the edges of the wound after removing large colon polyps. The goal is to see which method is faster while still preventing polyps from coming back. About 140 adults with large non-cancerous …

This study tests whether an artificial intelligence (AI) system can help doctors spot more precancerous polyps and colorectal cancers during colonoscopy compared to standard procedures. Over 3,300 adults scheduled for screening or surveillance will be randomly assigned to AI-assi…

Colonoscopy helps doctors find and remove polyps that can turn into bowel cancer, but the right side of the bowel often stays dirty even after standard preparation, so polyps there can be missed. This trial tests whether giving a small sodium phosphate enema into the right colon …

This trial tests two new imaging modes, VIST and SFI, during colonoscopy to see if they help doctors find and classify colorectal polyps better than standard white light. About 990 adults undergoing screening or surveillance colonoscopy will be randomly assigned to one of the thr…

This trial tests whether an AI system called GI Genius can help doctors accurately tell apart small colorectal polyps (5 mm or less) during a colonoscopy—identifying which ones are harmless versus those that need monitoring. For each small polyp, doctors first record their own di…

This study compares a new 3D colonoscopy with the standard 2D version to see which more accurately identifies polyps that could become colorectal cancer. About 600 adults undergoing colonoscopy will have their polyps examined with both methods, and the results will be checked aga…

This study tests whether spraying a mix of acetic acid and indigo carmine dye during colonoscopy helps doctors find more precancerous polyps (called sessile serrated lesions) in the right side of the colon compared to standard white-light colonoscopy. About 2,689 adults aged 45-8…

This study tests a new device that flattens colon polyps before they are examined under a microscope. The goal is to help doctors better identify sessile serrated lesions, a type of polyp that can lead to colorectal cancer. About 1,156 adults having polyps removed during a colono…

This study will check how well a non-invasive stool test (quantitative fecal immunochemical test, or qFIT) can detect colorectal cancer and precancerous lesions like adenomas and serrated polyps. Researchers will compare the test results with colonoscopy findings in 150 adults ag…

This study looks at whether people who have had large colon polyps removed can safely wait longer for their next colonoscopy. About 760 adults will be split into two groups: one getting the standard schedule (colonoscopy at 6, 18, and 48 months) and another getting a relaxed sche…

This study tests whether spraying a protective medication (sucralfate) on the wound after removing colon polyps can prevent delayed bleeding better than the standard method of placing clips. The trial will include 160 patients who take blood thinners and have large polyps. Partic…

This study tests whether letting patients give themselves sedation medication (propofol) by pressing a button during a colonoscopy leads to higher satisfaction than standard sedation given by a doctor. About 40 adults scheduled for colonoscopy will be randomly assigned to either …

This study tests whether a special imaging mode called RDI helps doctors remove early-stage cancers from the stomach, esophagus, or colon more quickly and safely than standard white-light endoscopy. About 158 adults with early cancers or precancerous lesions will be randomly assi…

This early study tests a new device that supports the colon wall during polyp removal. It involves 4 people who have a positive stool test and a polyp on the left side of the colon. The main goal is to see if the device can be placed successfully in one try.

This study looks at whether showing AI suggestions a few seconds later helps doctors make better decisions when diagnosing small colon polyps. Seventy endoscopists will watch 100 polyp videos, with some seeing AI advice right away and others seeing it after a delay. The goal is t…

This study tests a new short camera called a rectoscope to check the lower bowel after rectal tumour removal. The goal is to see if it can be used in the clinic with a simple enema instead of strong bowel prep, making follow-up checks faster and reducing waiting lists. Thirty pat…

This study looks at people who have had certain types of colon polyps (serrated lesions) removed. It aims to find out why some of them later develop new advanced growths in the colon. By tracking 750 adults over time, researchers hope to identify risk factors that could help doct…

This study looks at how often polyps in the stomach or colon grow back after being removed during a scope procedure. Researchers will follow about 2,000 adults for up to three years to track recurrence and identify risk factors like polyp size, lifestyle, and health history. The …

This study looks at whether a special decision aid helps patients with a cancerous colon polyp choose between more surgery or careful monitoring. About 110 adults in Denmark will use the aid during their doctor visit. The goal is to see if it changes treatment choices and improve…

This study tests whether an artificial intelligence (AI) system can help doctors in general hospitals accurately decide how to manage small colon polyps (5mm or smaller) during a colonoscopy. About 363 adults with at least one small polyp will be randomly assigned to have their p…

This study tests whether a computer-aided detection system can help doctors find more polyps in the right side of the colon during a colonoscopy. About 686 adults aged 40-75 will have two colonoscopies in one session, with the AI system used in one of them. The goal is to see if …