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Speed test: which heat tool best seals colon polyp removal sites?

NCT ID NCT07682805

Disease control Sponsor: Western Sydney Local Health District Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This trial compares two techniques—snare tip soft coagulation and hybrid APC—used to burn the edges of the wound after removing large colon polyps. The goal is to see which method is faster while still preventing polyps from coming back. About 140 adults with large non-cancerous colon polyps will take part. The main focus is on how long each technique takes, not on long-term cure rates.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
snare tip soft coagulation or hybrid APC (argon plasma coagulation)
What this could lead to
If one technique is faster and equally effective, it could become the standard method for preventing polyp regrowth after colonoscopy.
What could go wrong
This is a small, early-stage trial focused on procedure time, not long-term outcomes. The faster method may not prevent recurrence as well.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 140 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years * Undergoing piecemeal EMR of a non-pedunculated colorectal lesion ≥20 mm in size * Macroscopically complete resection achieved prior to margin ablation (no visible residual adenomatous tissue at the resection base) * Ability to provide written informed consent Exclusion Criteria: * Lesions requiring en bloc resection by ESD * Lesions with suspected deep submucosal invasion based on endoscopic assessment (e.g., depressed morphology, non-lifting sign, NICE type 3 pattern, or equivalent advanced imaging criteria) * Inflammatory bowel disease with active colitis at the lesion site * Overt invasive carcinoma requiring surgical management * Pregnancy * Inability to provide informed consent

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Conditions

The condition(s) this trial relates to.

adenomatous colon polyp colon adenoma colorectal adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colon adenomas Colon adenomatous polyp

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Westmead Hospital

    Sydney, New South Wales, 2145, Australia

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