Polyp of large intestine
MONDO:0021392A polyp that involves the large intestine.
Also known as: colorectal polyp, large bowel polyp, large intestine polyp, polyp of large bowel, polyp of the large bowel, polyp of the large intestine
95 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Cold vs. hot snare: which is better for removing colon polyps?
Disease control CompletedThis study compared two methods for removing non-cancerous colon polyps that are 10-19 mm in size: cold snare (no heat) and hot snare (uses heat). 216 adults undergoing colonoscopy were randomly assigned to one method. The goal was to see if cold snare is as effective and safe as…
Phase: NA • Sponsor: Qingwei Jiang • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Water-Assisted scope may improve colon polyp removal
Disease control CompletedThis trial tested a new method called underwater ESD for removing large, flat colon polyps. Instead of using gas to inflate the colon, doctors fill it with saline water. The goal was to see if this reduces complications like bleeding or perforation and improves complete removal. …
Phase: NA • Sponsor: Istituto Clinico Humanitas • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New device aims to cut surgery complications in colorectal patients
Disease control CompletedThis study tested whether a device that uses light to monitor blood flow (photoplethysmography) could help doctors manage fluids better during colorectal surgery. The goal was to reduce complications after surgery. 160 adults having colorectal surgery took part. The approach is n…
Phase: PHASE3 • Sponsor: University Hospital, Caen • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Herbal formula shows promise in preventing polyp return
Disease control CompletedThis study tested a traditional Chinese medicine formula called modified Si Ni San in 32 adults who had colorectal polyps removed. The goal was to see if the herbal treatment could improve gut bacteria balance and reduce inflammation better than standard probiotics. Results may h…
Phase: NA • Sponsor: Xi'an Hospital of Traditional Chinese Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Colon polyp showdown: which removal method wins?
Disease control CompletedThis study compared two procedures for removing large, flat colon polyps (over 25 mm) in 360 adults. One method, ESD, removes the polyp in one piece but has higher risks and costs. The other, EMR, removes it in pieces but is safer and cheaper. The goal was to see which leads to f…
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase: PHASE4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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AI eye on your colon: can software spot polyps better?
Diagnosis CompletedThis study tests whether a software called ColoMaia II can help doctors find abnormal growths (polyps) in the colon during a routine colonoscopy. About 600 adults aged 40 to 80 having a screening or diagnostic colonoscopy will be randomly assigned to have the procedure with or wi…
Phase: NA • Sponsor: MAIA Labs s.r.o. • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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AI helps doctors spot cancerous polyps during colonoscopy
Diagnosis CompletedThis study tested an artificial intelligence (AI) tool that helps doctors diagnose colorectal polyps during a colonoscopy. The AI analyzes images from a special high-magnification endoscope to predict whether a polyp is cancerous or not. The goal is to improve accuracy and reduce…
Sponsor: The First Hospital of Jilin University • Aim: Diagnosis
Last updated Jun 27, 2026 12:06 UTC
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3D camera could sharpen colonoscopy accuracy
Diagnosis CompletedThis completed trial tested whether a 3D imaging device helps doctors more accurately classify colon polyps and adenomas during colonoscopy compared to standard 2D imaging. 460 adults with colorectal polyps were randomly assigned to either 3D or 2D imaging before polyp removal. T…
Phase: NA • Sponsor: Xijing Hospital of Digestive Diseases • Aim: Diagnosis
Last updated Jun 27, 2026 11:03 UTC
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Laser ruler for colon polyps could sharpen cancer risk checks
Diagnosis CompletedThis study tested a new laser-based device (AccuMeasure) to measure the size of colon polyps during a colonoscopy. Accurate polyp size is important because it helps doctors decide how often patients need follow-up screenings to prevent colorectal cancer. The study involved 138 ad…
Phase: NA • Sponsor: Radboud University Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 09:10 UTC
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AI boosts polyp detection in colon cancer screening Follow-Up
Diagnosis CompletedThis study tested whether an AI tool (GI Genius) helps doctors find more polyps during colonoscopy in people aged 50-74 who had a previous polyp. Over 1,100 participants were randomly assigned to either AI-assisted or standard colonoscopy. The main goal was to see if AI increases…
Phase: NA • Sponsor: Fondazione Poliambulanza Istituto Ospedaliero • Aim: Diagnosis
Last updated Jun 27, 2026 09:05 UTC
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Blood test may spot colon cancer early, study shows
Diagnosis CompletedThis study tested a new blood test designed to find colorectal cancer early in people at average risk. Nearly 49,000 adults aged 45-85 gave a blood sample before their routine colonoscopy. The goal was to see how well the blood test could detect cancer and advanced growths compar…
Sponsor: Freenome Holdings Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC
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New colonoscope attachment aims to spot hidden polyps
Diagnosis CompletedThis study tested whether a device called Endocuff Vision, which attaches to the tip of a colonoscope and has soft projections to flatten folds in the colon, can help doctors find more sessile serrated adenomas—a type of precancerous polyp. Over 400 adults undergoing routine scre…
Phase: NA • Sponsor: University of California, Davis • Aim: Diagnosis
Last updated Jun 27, 2026 07:51 UTC
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AI helps doctors spot more polyps during colonoscopy
Diagnosis CompletedThis study tested whether an AI tool that highlights suspicious areas during colonoscopy helps doctors find more polyps. Over 400 adults aged 40-80 undergoing screening or diagnostic colonoscopy were randomly assigned to standard colonoscopy or AI-assisted colonoscopy. The main g…
Phase: NA • Sponsor: Gian Eugenio Tontini • Aim: Diagnosis
Last updated Jun 26, 2026 16:05 UTC
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Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Study reveals what makes patients happier during cancer screening
Knowledge-focused CompletedThis study looked at 846 people who had a positive stool test for colorectal cancer and needed a follow-up colonoscopy. Researchers wanted to understand how involved patients felt in making decisions about their care and how satisfied they were with the entire screening and treat…
Sponsor: Corporacion Parc Tauli • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Which position makes colonoscopy easier? new study investigates
Knowledge-focused CompletedThis study tested whether starting a colonoscopy with the patient lying on their back (supine) or on their left side (left-lateral) makes a difference. Researchers measured how long it took to complete the procedure, how much pain patients felt, and how difficult the procedure wa…
Phase: NA • Sponsor: Celal Bayar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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AI learns from 600 colonoscopies to spot polyps
Knowledge-focused CompletedThis study gathered real-world videos and images from 600 adults undergoing screening or surveillance colonoscopies. The data will be used to develop and test artificial intelligence systems that can help doctors detect colon polyps. The study is complete and focused on data coll…
Sponsor: Olympus Europe SE & Co. KG • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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New device aims to sharpen polyp measurements for trainee doctors
Knowledge-focused CompletedThis study tested a device called Napoleon to help gastroenterology fellows measure colon polyps more accurately during colonoscopies. 46 patients aged 45 and older participated. The goal was to see if using the device improves measurement accuracy compared to just looking, which…
Phase: EARLY_PHASE1 • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Quick video training boosts cancer detection in polyps, study finds
Knowledge-focused CompletedThis study tested whether a short training video on 'blink features' (visual clues like redness or ulcers) could help medical students and non-gastroenterology trainees better detect cancer in images of colon polyps. 65 participants completed an online survey before and after wat…
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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AI boosts polyp detection in colonoscopy: over 5,000 tested
Knowledge-focused CompletedThis completed study tested whether an AI system called GI Genius helps doctors spot polyps during colonoscopy. Over 5,000 adults participated. The goal was to see if AI improves detection rates and whether using AI has a lasting learning effect. Results could lead to better colo…
Phase: NA • Sponsor: Haraldsplass Deaconess Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Bacteria in mouth and gut may hold clues to colon polyp risk
Knowledge-focused CompletedThis study looked at the bacteria in the mouth and gut of 126 people with and without serrated polyposis syndrome, a condition that raises the risk of colorectal cancer. Researchers compared the bacteria in people with the syndrome to those with other types of polyps or no polyps…
Sponsor: Hospital Universitari Vall d'Hebron Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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8,000 volunteers help uncover colon polyp risks
Knowledge-focused CompletedThis study looked at why some people develop colorectal polyps (growths that can turn into cancer) and others do not. Researchers collected blood, urine, saliva, and tissue samples from over 8,000 adults getting a colonoscopy. They also gathered information about lifestyle and he…
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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AI timer boosts polyp detection during colonoscopy
Knowledge-focused CompletedThis study tested whether an artificial intelligence system that tracks how long doctors spend examining the colon during a colonoscopy could help them find more polyps. Researchers enrolled 193 adults aged 40 and older undergoing outpatient colonoscopy. The AI calculated effecti…
Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:46 UTC