Cold vs. hot snare: which is better for removing colon polyps?

NCT ID NCT05545787

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compared two methods for removing non-cancerous colon polyps that are 10-19 mm in size: cold snare (no heat) and hot snare (uses heat). 216 adults undergoing colonoscopy were randomly assigned to one method. The goal was to see if cold snare is as effective and safe as hot snare for complete removal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cold snare endoscopic mucosal resection and hot snare endoscopic mucosal resection

What this could lead to

If successful, this could show that cold snare removal is just as effective as hot snare but with fewer risks, improving colon polyp treatment.

What could go wrong

This is a completed trial with 216 participants, but results may not apply to larger polyps or other populations. Both procedures carry risks like bleeding or perforation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

polyp of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Daxing District People's Hospital

    Beijing, Beijing Municipality, 102600, China

  • Beijing Dongcheng District First People's Hospital

    Beijing, Beijing Municipality, 100010, China

  • Beijing Fangshan District Liangxiang Hospital

    Beijing, Beijing Municipality, 102401, China

  • Beijing Sixth Hospital

    Beijing, Beijing Municipality, 100191, China

  • Beijing Tsinghua Changgung Hospital

    Beijing, Beijing Municipality, 102218, China

  • Emergency General Hospital

    Beijing, Beijing Municipality, 100028, China

  • Henan Provincial People's Hospital

    Zhengzhou, Henan, 450003, China

  • PLA Western Theater General Hospital

    Chengdu, Sichuan, 610083, China

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100730, China

  • Seventh Medical Center, General Hospital of the Chinese People's Liberation Army

    Beijing, Beijing Municipality, 100700, China

  • The Affiliated Hospital of Qingdao University

    Qingdao, Shandong, 266005, China

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 400016, China

  • The First Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, 330006, China

  • The First Hospital of Shanxi Medical University

    Taiyuan, Shanxi, 030001, China

  • West China Longquan Hospital, Sichuan University

    Chengdu, Sichuan, 610041, China