New blood test could spot colon cancer before it spreads
NCT ID NCT06342440
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a new blood test called DENEB that looks for tiny molecules (microRNAs) to find colorectal cancer and precancerous polyps early. Researchers will collect blood samples from 2,000 people who are also getting a colonoscopy. The goal is to see if the blood test is accurate and could one day offer a simpler, less invasive way to screen for colorectal cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DENEB blood test (measures microRNA levels)
What this could lead to
If successful, this blood test could offer a simple, non-invasive way to catch colorectal cancer and precancerous polyps early, potentially saving lives through earlier treatment.
What could go wrong
This is an early-stage study still recruiting participants. The test may not be accurate enough to replace colonoscopy, and results may not apply to everyone.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Locations
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Barcelona University
RECRUITINGBarcelona, Spain
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Contact Email: •••••@•••••
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City of Hope Medical Center
RECRUITINGMonrovia, California, 91016, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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IRCCS San Raffaele
RECRUITINGMilan, Italy
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Mie University
RECRUITINGMie, Japan
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The First Affiliated Hospital of Dalian Medical University
RECRUITINGDalian, China
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University of California San Diego
RECRUITINGSan Diego, California, 92093, United States
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