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Web tool aims to spot hidden cancer in large colon polyps without special equipment

NCT ID NCT07705880

Knowledge-focused Sponsor: University Hospital, Ghent Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study tests a simple web-based tool that helps doctors predict whether a large colon polyp contains invasive cancer. The tool uses only standard endoscopic images and basic information like polyp size and location. Doctors of varying experience will use the tool to assess polyps before and after a short training session, and their accuracy will be compared to expert opinion. If the tool works well, it could make cancer detection easier and more consistent across hospitals.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a web-based clinical decision support tool
What this could lead to
If successful, this tool could help doctors quickly and accurately decide whether a large colon polyp can be removed during colonoscopy or requires surgery, potentially reducing unnecessary procedures.
What could go wrong
The tool is still being tested and may not be more accurate than current methods. Its performance depends on the training doctors receive, and results may vary across different hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 886 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2022

Expected to finish

Sep 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with large (≥20mm) non-pedunculated colorectal polyps (LNPCPs) detected during colonoscopy or referred for endoscopic resection. Patients with sessile serrated lesions are excluded. Endoscopists must consent and complete the learning intervention. Patients must provide written informed consent for data collection. Participation is voluntary for both groups.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Endoscopist participants * Gastrointestinal endoscopists of varying abilities and grades * Endoscopists who have not previously encountered the clinical decision support tool Patient participants * Referred for colonoscopy with appropriate bowel preparation * Colorectal polyp \>=20mm in size detected or referred for resection * Non-pedunculated morphology * Non-sessile serrated morphology * Signed informed consent for the procedure and trial participation Exclusion Criteria: Endoscopist participants: * Does not consent to inclusion * Does not undergo the learning intervention * No connection with endoscopy in gastroenterology Patient participants: * Does not consent to data collection for the study * Video of inadequate quality as per opinion of the principal investigator

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Conditions

The condition(s) this trial relates to.

colorectal neoplasm polyp of colon polyp of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colonic polyps Colorectal neoplasms

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • UZ Gent

    RECRUITING

    Ghent, 9000, Belgium

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