Water-Assisted scope may improve colon polyp removal
NCT ID NCT07040020
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tested a new method called underwater ESD for removing large, flat colon polyps. Instead of using gas to inflate the colon, doctors fill it with saline water. The goal was to see if this reduces complications like bleeding or perforation and improves complete removal. 122 adults with polyps larger than 20mm took part. The study compared the underwater approach to the standard gas-based technique.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Underwater ESD (U-ESD) procedure
What this could lead to
If successful, this could make removing large colon polyps safer and more effective, reducing the need for surgery.
What could go wrong
This is a completed trial with 122 participants, so results are limited in size. The underwater technique may not prove superior for all polyp types or settings.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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IRCCS Humanitas Research Hospital
Rozzano, MI, 26900, Italy