Heat treatment after polyp removal may slash regrowth risk
NCT ID NCT07242820
First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study tests whether adding a heat treatment (thermal ablation) to the standard procedure for removing large colon polyps can lower the chance they grow back. About 752 adults will be randomly assigned to receive either standard removal alone or standard removal plus burning of the edges and base of the site. Participants will be followed for 18 months with two follow-up colonoscopies to check for recurrence and any side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- adjuvant thermal ablation (a procedure that uses heat to burn the edges and base of the polyp removal site)
- What this could lead to
- If it works, this could become a standard step during colonoscopy to reduce the chance that large polyps grow back.
- What could go wrong
- This is a relatively early-stage procedure comparison, not a new drug. The benefit may be small, and there is a risk of bleeding or perforation from the extra burning.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre Hospitalier de l'Université de Montréal
Montreal, Quebec, Canada
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