Heat treatment after polyp removal may slash regrowth risk

NCT ID NCT07242820

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a heat treatment (thermal ablation) to the standard procedure for removing large colon polyps can lower the chance they grow back. About 752 adults will be randomly assigned to receive either standard removal alone or standard removal plus burning of the edges and base of the site. Participants will be followed for 18 months with two follow-up colonoscopies to check for recurrence and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

adjuvant thermal ablation (a procedure that uses heat to burn the edges and base of the polyp removal site)

What this could lead to

If it works, this could become a standard step during colonoscopy to reduce the chance that large polyps grow back.

What could go wrong

This is a relatively early-stage procedure comparison, not a new drug. The benefit may be small, and there is a risk of bleeding or perforation from the extra burning.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm polyp of colon polyp of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier de l'Université de Montréal

    Montreal, Quebec, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••