Pelvic varices

This study tests whether sending patients home on the same day of surgery, with follow-up care via phone calls, home visits, and a mobile app, is as safe and less costly than keeping them in the hospital overnight. The trial includes adults in Uganda having low-risk procedures su…

This study compares two surgical techniques for hemorrhoids: Doppler-guided artery ligation alone versus the same procedure combined with mucopexy (stitching up the prolapsed tissue). Researchers will measure pain levels and the sensation of incomplete evacuation (tenesmus) in 15…

This trial investigates whether AI-assisted written patient information, given alongside standard medical treatment, helps adults with mild to moderate hemorrhoids follow their treatment plan more completely. Participants receive either standard verbal counseling or an AI-generat…

This study looks at how surgery to fix varicocele—enlarged veins in the scrotum—affects the number of immature sperm cells in semen. Infertile men aged 20 to 45 with varicocele will have a microsurgical procedure to tie off the abnormal veins. Their semen will be tested before su…

The BRIGHT study will follow 250 adults with grade II-III hemorrhoids who are treated with a procedure called hemorrhoid artery embolization (HAE). This technique uses tiny metal coils to block blood flow to the hemorrhoids, aiming to stop bleeding without major surgery. Research…

This study tests whether a type of abdominal massage called visceral osteopathic manual therapy can improve sperm quality and blood flow in men with varicocele, a condition where veins in the scrotum become enlarged and can cause infertility. Thirty-two men aged 18-45 will either…

This study tests a more thorough varicocele surgery that strips away extra veins, compared to the standard method. About 160 infertile men with varicocele will be randomly assigned to one of the two procedures. The goal is to see if the extended stripping reduces the chance of va…

This trial tests a new surgical technique called low excision and high suspension hemorrhoidectomy against the standard Milligan-Morgan procedure for people with severe grade III-IV mixed hemorrhoids. The study will include 120 adults who have not improved with other treatments. …

This study translates two standard questionnaires—the Hemorrhoidal Disease Symptom Score and the Short Health Scale for Hemorrhoidal Disease—into Mandarin Chinese and checks whether they are reliable and accurate for Chinese-speaking patients with hemorrhoids. About 115 adults di…

This study tests whether placing an ice pack inside the anal canal for one minute right after hemorrhoid removal surgery can reduce pain. Adults with severe (grade III or IV) hemorrhoids will be randomly assigned to receive either standard surgery alone or surgery plus this quick…

This study tests whether Shouhui Tongbian Capsules, a traditional Chinese herbal medicine, can relieve constipation after surgery for benign anal or rectal conditions like hemorrhoids. 120 adults will be randomly assigned to take either the herbal capsules or a standard laxative …

This study tests a new pain management system for people recovering from incarcerated mixed hemorrhoid surgery. The system includes pain medicine before surgery, traditional Chinese medicine treatments, and personalized nursing. Researchers want to see if it reduces pain and comp…

This study tests whether taking oral nifedipine, a drug usually used for high blood pressure, can reduce pain and improve wound healing after hemorrhoid removal. One hundred adults in Yemen will receive either nifedipine or a placebo twice daily for two weeks after surgery. Resea…

This study tests whether a daily herbal capsule called Nimsai Herbal can shrink hemorrhoids and reduce symptoms like pain and itching. Fifty adults with grade 2-3 hemorrhoids will take either the herbal blend or a placebo for 10 days. The main goal is to see if the hemorrhoids im…

This study looks at whether a supplement called MPFF (micronized purified flavonoid fraction) can help reduce pain and improve quality of life in adults with grade 2 or 3 hemorrhoids who are having a minor surgical procedure. About 200 participants will take MPFF as part of their…

This study compares three methods of closing the wound after hemorrhoid removal: leaving it open, stitching it closed, or stitching only half closed. About 378 adults with mixed hemorrhoids needing surgery will be randomly assigned to one of the three groups. Researchers will mea…

This study tests whether nitroglycerin ointment, a drug often used for chest pain, can reduce pain after rubber band ligation for internal hemorrhoids. About 68 adults with grade I-III hemorrhoids will apply the ointment or a placebo three times daily for two weeks after the proc…

This study tests if acupuncture can lower pain and the need for painkillers after hemorrhoid removal. About 100 adults having surgery for severe hemorrhoids will get either real acupuncture or a sham version over 5 days. Researchers will track pain levels, medication use, and rec…

This study compares two sedative drugs, dexmedetomidine and ketamine, given before spinal anesthesia for varicocele surgery. The goal is to see which one provides better sedation and fewer side effects. The trial will involve 58 men aged 18 to 40.

This trial tests whether protecting the anal canal during pelvic radiation can reduce hemorrhoid-related symptoms like pain, bleeding, and discomfort in cervical cancer patients. 300 women who had a hysterectomy and need radiation will be randomly assigned to standard radiation o…

This study tests whether getting more frequent phone check-ins after hemorrhoid surgery helps patients feel better and avoid problems. 116 adults who had hemorrhoid surgery will be split into two groups: one gets standard follow-up calls, the other gets extra calls. Researchers w…

This study tests whether adding methylene blue to a standard painkiller can reduce pain after hemorrhoid surgery. About 177 adults with severe hemorrhoids will receive one of two doses of methylene blue plus ropivacaine. Researchers will track pain scores, painkiller use, and qua…

This study will follow 120 women having surgery for common anal conditions like fissures, hemorrhoids, or fistulas. Researchers want to see if their sexual function improves after surgery. Participants will fill out questionnaires before surgery and at 3 and 6 months after. The g…

This study will follow 100 people with severe obesity who are starting a GLP-1 drug (like Ozempic or Wegovy) to see if it causes new anal or rectal problems within the first 3 months. Participants will have a check-up before starting the drug and again after 3 months to look for …

This study will test whether using a minimally invasive surgical technique for advanced hemorrhoid removal can reduce pain and speed up recovery. Fifty adults with grade III or IV hemorrhoids will undergo the procedure, and researchers will track how well the technique can be rep…

This study looks at 40 infertile men with varicoceles (enlarged veins in the scrotum) to see if blood flow measurements in the testicles can predict how well they will respond to surgery. Participants will have ultrasound and blood tests before and three months after a standard m…

This study looks at 100 men with varicoceles (enlarged veins in the scrotum) to see if the amount of backward blood flow affects sperm quality. Participants will have ultrasound and semen tests before and 3 months after varicocele repair surgery. The goal is to better understand …