Could a heart drug ointment soothe hemorrhoid pain?

NCT ID NCT07391501

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether nitroglycerin ointment, a drug often used for chest pain, can reduce pain after rubber band ligation for internal hemorrhoids. About 68 adults with grade I-III hemorrhoids will apply the ointment or a placebo three times daily for two weeks after the procedure. The main goal is to see if fewer people need rescue pain medication within 72 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nitroglycerin ointment

What this could lead to

If it works, this could provide a simple, safe way to ease pain after a common hemorrhoid procedure, reducing the need for extra painkillers.

What could go wrong

This is a small, early-phase trial. The ointment may not work better than placebo, and side effects like headache or low blood pressure are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

internal hemorrhoid Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••