Patellofemoral pain syndrome

This study compares two types of hip replacement materials in 100 adults aged 18 to 65 who need a total hip replacement. One group gets a ceramic-on-polyethylene implant where the polyethylene is infused with vitamin E to reduce wear. The other group gets a standard ceramic-on-ce…

This study compares three types of knee-strengthening exercises (isometric, isotonic, and eccentric) in 90 adults aged 18-40 with patellofemoral pain syndrome. Participants will do their assigned exercises three times a week for 8 weeks, alongside standard physiotherapy. Research…

This study compares a mobile app-based rehabilitation program to traditional in-person physiotherapy for recreational athletes aged 18–35 with patellofemoral pain syndrome (pain around the kneecap). Both groups follow the same exercise plan for four weeks, but one group does it r…

This study compares Kinesio taping and McConnell taping in people aged 18–50 with patellofemoral pain syndrome (front knee pain). Participants will receive one of the taping methods plus a 6-week exercise program, or just exercise alone. Researchers will measure muscle activation…

This study compares two exercise methods that use a cuff to partly restrict blood flow to the leg: resistance training with light weights versus stationary cycling. Both aim to reduce pain and improve strength in athletes with patellofemoral pain syndrome. Forty-eight athletes ag…

This study compares two treatments for patellofemoral pain syndrome (knee pain): releasing the popliteus muscle versus applying kinesio tape. About 48 adults aged 18-30 with at least 3 months of knee pain will be enrolled. The goal is to see which approach better reduces pain, im…

This study tests a new exercise approach for people with patellofemoral pain syndrome (runner's knee). It combines isokinetic training with blood flow restriction to see if it reduces pain and improves knee function. The study involves 60 adults aged 18 to 40 who have had knee pa…

This study looks at whether following specific clinical guidelines for treating patellofemoral pain (a common knee problem) works better than usual physical therapy. About 440 active-duty military members will take part. Researchers will compare knee function, pain levels, and co…

This study tests two ways to manage pain after hip replacement surgery. One group gets a nerve block plus a second nerve block; the other gets a nerve block plus wound numbing. The goal is to see which method reduces pain and the need for opioid painkillers. About 102 adults havi…

This study looks at whether whole-body vibration therapy can reduce knee pain in people who still have pain after ACL reconstruction surgery. About 50 adults aged 18 to 60 with ongoing kneecap pain will use a vibrating platform for 8 weeks. The goal is to see if this simple train…

This study looks at whether dry needling can ease knee pain and improve leg strength and function in people with patellofemoral pain syndrome (pain around the kneecap). Researchers will give dry needling treatments to 120 adults aged 18 to 40 and measure changes in pain and movem…

This study looks at whether telling people to focus on their muscles (internal focus) or on an external object (external focus) during knee exercises leads to better strength and less pain. Researchers will enroll 36 adults with patellofemoral pain syndrome and track their progre…

This study tests a manual therapy technique called saphenous nerve release to see if it can reduce pain, improve balance, and restore function in people with patellofemoral pain syndrome (a common cause of front knee pain). The trial will include 36 adults aged 18 to 35 with pers…

This study uses MRI and ultrasound to watch how muscles, tendons, and bones work together when you move. Researchers hope to learn what normal and injured movement looks like, which could lead to better ways to diagnose and treat problems like knee pain. Healthy volunteers and pe…

This study will follow 200 people who have had a complex or revision hip replacement at University Hospitals Leuven. The goal is to track how many need another surgery and why, and to improve care by learning from real-world results. No new treatment is being tested—this is an ob…

This study is looking at how the shape and alignment of the kneecap joint relate to knee pain. Researchers will take 3D CT scans of the knee while people stand (weight-bearing) to see the joint in a natural position. They hope to find links between specific bone measurements and …

This study follows 850 people aged 10–35 who are having surgery for a kneecap that keeps dislocating. Researchers want to find out what factors increase the risk of the kneecap dislocating again after surgery. Participants will fill out surveys about their knee function and activ…

This study tests whether an online education tool is a practical option for people with patellofemoral pain (knee pain) who are waiting for physiotherapy. Researchers will recruit 40 adults aged 18-44 and see if they can complete the online modules and questionnaires. The goal is…

This study looks at how limited ankle movement affects a single-leg squat in people with long-term knee pain (patellofemoral pain). Researchers will measure ankle flexibility and pain during daily activities. The goal is to better understand the link between ankle tightness and k…

This study looks at how often people can return to sports at least three years after total knee replacement. It compares three different types of knee prostheses to see if one type leads to better sports participation. The study will include 660 adults who had their first knee re…

This study looks at how bending the knee during exercises like squats affects pain in people with patellofemoral pain syndrome (PFPS). Fifteen participants will do three types of squats with increasing range of motion and rate their pain. The goal is to understand the relationshi…