Patellofemoral pain syndrome

This study compares two types of hip replacement materials in 100 adults aged 18 to 65 who need a total hip replacement. One group gets a ceramic-on-polyethylene implant where the polyethylene is infused with vitamin E to reduce wear. The other group gets a standard ceramic-on-ce…

This study compares Kinesio taping and McConnell taping in people aged 18–50 with patellofemoral pain syndrome (front knee pain). Participants will receive one of the taping methods plus a 6-week exercise program, or just exercise alone. Researchers will measure muscle activation…

This study compares two exercise methods that use a cuff to partly restrict blood flow to the leg: resistance training with light weights versus stationary cycling. Both aim to reduce pain and improve strength in athletes with patellofemoral pain syndrome. Forty-eight athletes ag…

This study compares two treatments for patellofemoral pain syndrome (knee pain): releasing the popliteus muscle versus applying kinesio tape. About 48 adults aged 18-30 with at least 3 months of knee pain will be enrolled. The goal is to see which approach better reduces pain, im…

This study tests a new exercise approach for people with patellofemoral pain syndrome (runner's knee). It combines isokinetic training with blood flow restriction to see if it reduces pain and improves knee function. The study involves 60 adults aged 18 to 40 who have had knee pa…

This study looks at whether doing breathing exercises before orthopedic surgery (like knee, hip, or fracture repair) can help your lungs work better after the operation. It involves 36 adults who have used tobacco and are at risk for breathing problems after surgery. Participants…

This study looks at whether following specific clinical guidelines for treating patellofemoral pain (a common knee problem) works better than usual physical therapy. About 440 active-duty military members will take part. Researchers will compare knee function, pain levels, and co…

This study tests two ways to manage pain after hip replacement surgery. One group gets a nerve block plus a second nerve block; the other gets a nerve block plus wound numbing. The goal is to see which method reduces pain and the need for opioid painkillers. About 102 adults havi…

This study looks at whether whole-body vibration therapy can reduce knee pain in people who still have pain after ACL reconstruction surgery. About 50 adults aged 18 to 60 with ongoing kneecap pain will use a vibrating platform for 8 weeks. The goal is to see if this simple train…

This study tests whether a program of exercise and ergonomics training can reduce muscle and joint pain in teachers. About 80 teachers who have had pain for at least three months will be randomly assigned to receive the training or not. Researchers will measure changes in pain, d…

This study looks at whether dry needling can ease knee pain and improve leg strength and function in people with patellofemoral pain syndrome (pain around the kneecap). Researchers will give dry needling treatments to 120 adults aged 18 to 40 and measure changes in pain and movem…

This study looks at whether telling people to focus on their muscles (internal focus) or on an external object (external focus) during knee exercises leads to better strength and less pain. Researchers will enroll 36 adults with patellofemoral pain syndrome and track their progre…

This study tests a web-based app called IAMABLE that provides evidence-based rehabilitation strategies for people with chronic conditions like heart disease, arthritis, or neurological disorders. Fifty adults aged 45 to 75 will use the app for 4 months to set goals and learn abou…

This study tests a manual therapy technique called saphenous nerve release to see if it can reduce pain, improve balance, and restore function in people with patellofemoral pain syndrome (a common cause of front knee pain). The trial will include 36 adults aged 18 to 35 with pers…

This study tests whether extra support for case managers helps veterans leaving the military better manage pain and reduce risky substance use. About 1800 veterans will take part. The program focuses on non-drug pain treatments and counseling.

This study uses MRI and ultrasound to watch how muscles, tendons, and bones work together when you move. Researchers hope to learn what normal and injured movement looks like, which could lead to better ways to diagnose and treat problems like knee pain. Healthy volunteers and pe…

This study aims to learn more about rare skeletal disorders by collecting medical records, blood samples, and genetic data from 100 participants. People with known or suspected bone conditions, as well as their healthy family members, can join either remotely or in person. The go…

This study translates and tests several health questionnaires—covering pain, arm and leg function, mood, and daily activities—for use with Albanian-speaking people. Researchers will check if the translated versions are reliable and accurate by giving them to about 300 participant…

This study tests a new tool called the PRISM Dashboard, which gives physiotherapists feedback on how their decisions compare to their peers. The goal is to see if this feedback helps reduce differences in care for people with muscle and joint pain. About 60 physiotherapists and t…

This study is looking at how the shape and alignment of the kneecap joint relate to knee pain. Researchers will take 3D CT scans of the knee while people stand (weight-bearing) to see the joint in a natural position. They hope to find links between specific bone measurements and …

This study follows 252 adults with muscle, bone, or joint problems (like arthritis, back pain, or after surgery) to see how well they do their prescribed home exercises. Researchers will track who sticks with the program and why, looking at factors like pain, mood, and support. T…

This study tests whether using a virtual reality (VR) headset during shoulder exercises helps patients feel more engaged and motivated. Fifty adults with shoulder problems will do rehab exercises in a VR environment and then answer questionnaires about how easy and immersive the …

This study follows 850 people aged 10–35 who are having surgery for a kneecap that keeps dislocating. Researchers want to find out what factors increase the risk of the kneecap dislocating again after surgery. Participants will fill out surveys about their knee function and activ…

This study tests whether an online education tool is a practical option for people with patellofemoral pain (knee pain) who are waiting for physiotherapy. Researchers will recruit 40 adults aged 18-44 and see if they can complete the online modules and questionnaires. The goal is…

This study aims to create a secure national database for muscle and joint (musculoskeletal) conditions by collecting routine data from community clinics and GP practices. About 22,000 adults will have their information anonymously gathered to help develop a dashboard that tracks …

This study looks at how limited ankle movement affects a single-leg squat in people with long-term knee pain (patellofemoral pain). Researchers will measure ankle flexibility and pain during daily activities. The goal is to better understand the link between ankle tightness and k…

This study watches 2000 people having hip or knee replacement surgery to see how long spinal anaesthesia lasts. The goal is to learn how the amount of anaesthetic affects timing, helping doctors decide if patients can safely go home the same day. No new treatments are tested—just…

This study looks at how often people can return to sports at least three years after total knee replacement. It compares three different types of knee prostheses to see if one type leads to better sports participation. The study will include 660 adults who had their first knee re…

This study looks at how changing the heel cushion on an ankle-foot brace (AFO) affects walking in people who use one daily. Forty adults with leg injuries or nerve problems will try four different heel wedges—tall or short, soft or firm—while walking at controlled speeds. Researc…

This study looks at how 3D computer simulation and printing can help surgeons better plan and perform bone correction surgeries. Researchers will compare the planned corrections to the actual results in 100 children and young adults with rare bone deformities. The goal is to make…

This study looks at how bending the knee during exercises like squats affects pain in people with patellofemoral pain syndrome (PFPS). Fifteen participants will do three types of squats with increasing range of motion and rate their pain. The goal is to understand the relationshi…

This study follows 4,000 children who receive orthopedic implants (like rods or screws) during standard care for bone fractures, deformities, or hip problems. Researchers will track how long the implants last, any complications, and how well they work over time. The goal is to ga…

This study is building a registry of people with rare bone diseases (skeletal dysplasias) in Italy. Researchers will collect medical history, genetic data, and treatment details over time to better understand how these conditions progress. No experimental treatments are given; th…

This study follows 144 adults with muscle or bone problems who are already scheduled to receive treatment with Chattanooga Intelect devices (like TENS or ultrasound). Researchers will measure pain, muscle strength, and movement range to confirm the devices are safe and work as ex…